Molecular biology is a mandatory course for biology undergraduates at Universidade Federal Fluminense. To overcome the impossibility of practical activities, we proposed problem‐solving synthetic biology assignments to review and consolidate the knowledge acquired in the molecular biology course. A survey ...
Synthetic biology has reached the same inflection point achieved by computer science in the 1950's The foundational pieces emerging, in the form of standardized DNA parts, packaged for combinatoric assembly using standards such as BioBricks. But: Creating new DNA parts is tedious and time-...
This use of the term is an extension of the concept of 'biomimetic chemistry', in which organic synthesis is used to create artificial molecules that recapitulate the behaviour of parts of biology, typically enzymes6. Synthetic biology has a broader scope, however, in that it attempts to ...
On ABC TV, the six-part science documentary series " Searching For Superhuman " Dr Shalin Naik a cell biologist focused on the building blocks of life - immunology and developmental biology, explors the most ambitious biological research project in history, the race to decode the human genome,...
synthetic lethality cancer biology CRISPR tumor suppressor genes cancer evolution Introduction CRISPR-Cas9 technology has revolutionized functional genomics by enabling high-fidelity, genome-scale, multiplexed loss-of-function screens in human cells. Because of high specificity and ease of application, genome...
Producing multi-component products such as vaccines could also circumvent the issue of undesirable background production, as multiple products could be expressed from a single strain. Furthermore, synthetic biology could help tailor a vaccine for specific populations, as different antigens are likely to...
Advances in synthetic biology tools and engineering of Corynebacterium glutamicum as a platform host for recombinant protein production. Biotechnol Bioproc E. 2023;28(6):962–76. Article CAS Google Scholar Freudl R. Beyond amino acids: Use of the Corynebacterium glutamicum cell factory for the ...
Antheia is a synthetic biology company developing rapid-response biomanufacturing processes for Active Pharmaceutical Ingredients and Key Starting Materials. In this session, Christina Smolke, PhD, CEO and co-founder of Antheia will dive into synthetic biology as a manufacturing technology and its ...
10.1038/ncomms11247 OPEN A programmable synthetic lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like cells Pratik Saxena1, Boon Chin Heng1,w, Peng Bai1, Marc Folcher1, Henryk Zulewski1,2,w & Martin Fussenegger1,3 Synthetic biology has advan...
protein, and each construct’s thermal half-life was determined by assuming (i) that unfolding followed a first-order exponential decay (which agreed well with all unfolding curves over the time course of the experiment) and (ii) that the 95 °C average baseline represents 100% unfolded ...