A recently proposed ACS catalytic mechanism involves a zero valent nickel as the complex to accept a methyl group from methylcobalt species during catalytic turnover.2 Synthetic analog studies were designed to probe the feasibility of Ni(0) as the methyl acceptor. Reaction of [triphos]Ni(PPh3) ...
We noted a sequence homologous to hFSH-beta-(1-15) between residues 7 to 21 of the beta-subunits of both hLH and hCG. A peptide amide representing this region of hLH-beta (hLH-beta-(7-21)) and an N-terminal truncated analog (hLH-beta-(10-21)) that more closely resembles the ...
In biomedical research, ovulation induction is a critical step in the reproductive biology of laboratory animals. This study evaluates the efficacy of peforelin, a synthetic gonadotropin-releasing hormone (GnRH) analog, in comparison to pregnant mare serum gonadotropin (PMSG, synonym: eCG), traditiona...
Synthesis of the C1-phosphonate analog of UDP-GlcNAc. Carbohydr. Res. 2006, 341, 1998–2004. [CrossRef] [PubMed] 12. Hajduch, J.; Nam, G.; Kim, E.J.; Fröhlich, R.; Hanover, J.A.; Kirk, K.L. A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its ...
The corresponding capU strain was unable to produce the L-ACL-containing A-503083 A (6) and A- 503083 B (7) but instead produced relatively high levels of the deaminocaprolactam analog A-503083 Molecules 2019, 24, 433 6 of 17 A-503083s. Unfortunately, additional attempts to make ...
2.2. Effects of Semi-Synthetic SL Derivatives on TCR Activation To assess the biological activity of the 11 semi-synthetic SL analogs and a natural analog of argolide (dihydroargolide or ketopelenolide B), we evaluated their effects on TCR activation-induced responses in Jurkat T cells and ...