Benzoic acidSynthesisSolar Thermal Electrochemical Process (STEP) synthesis of benzoic acid from toluene using a platinum anode has been developed as high yield and selectivity using the full spectrum of sunlight. STEP organic is an efficient process for organic synthesis based upon its use of a ...
Methylbenzene, commonly referred to as toluene, is an aromatic hydrocarbon characterised by a methyl group attached to a benzene ring. This structural aspect significantly influences its chemical behaviour, laying the groundwork for its conversion to benzoic acid. Characteristics of Methylbenzene Molecular...
Silica sulfuric acid was used as the catalyst for the synthesis of n-butyl benzoate from benzoic acid and butanol.Effects of catalyst dosage,molar ratios of the reactants and reaction time were investigated by using single-factor experimental method.The optimum conditions was found as follows: 1.6...
To analyze substrate specificity of PhBS, CoA esters were enzymatically synthesized from structural analogs of benzoic acid including cinnamic acid, para-coumaric acid, caffeic acid, ferulic acid and sinapic acid using purified recombinant petunia 4-coumarate:CoA ligase (Ph4CL1) (Supplementary Fig. 5b...
(Fig.4). To our delight, when the crude Michael adduct8was treated withp-toluenesulfonic acid in toluene at 90 °C, the desired product10was isolated in 66% yield without the loss of enantioselectivity (94% ee). It should be noted that its enantiopurity can be further enhanced after ...
could be achieved by using more cyclohexanone (11a), pyrrolidine (12a), and benzoic acid (13a) (3.0, 0.30, and 0.30 equiv., respectively) (Table 1, entry 12). Control reactions conducted under these conditions without either NHPI (2a),4b,11a,12a, or13aall failed to give any of the de...
Fig. 5. Cytotoxicity of deoxyadenosine-bile acid 1,2,3-triazoles conjugates (81, 82 & 83) as anticancer agents. 2. Synthesis and anticancer activity of steroid-triazoles conjugates It has been well understood that the presence of different functional groups around the rigid tetracyclic steroidal ...
(b) Lewis acid-promoted and phosphine-catalysed [3 þ 2] cycloaddition of allenoates to construct five-membered carbocycles. (c) Our strategy to access both [3.3.0] and [4.3.0] bicyclic ring systems via Rh- catalysed [3 þ 2] cycloaddition. 2 NATURE COMMUNICATIONS | 5:5707 | DOI:...
Fig. 2: Substrate scope of the reaction a. aReactions were carried out with 0.1‒0.2 mmol of substrate 1, catalyst 6d (5 mol %), acetic acid (1 equiv.) in toluene at the specified temperature for the specified time. Yields are for the isolated compounds. The enantiomeric ratios...
a) subjecting a compound of the formula ##STR20## (where X=Cl or Br) to tributyltin hydride in the presence of AIBN in Toluene to yield a compound of the formula: ##STR21## and b) treating the product of step (a) with acid to deprotect the stereocontrolling protecting group at ...