alpha,beta-Unsaturated ketones are common feedstocks for the synthesis of fine chemicals, pharmaceuticals, and natural products. Transition metal-catalysed hydroacylation reactions of alkynes using aldehydes have been recognised as an atom-economical route to access alpha,beta-unsaturated ketones through ...
SYNTHESIS OF ALPHA,BETA-UNSATURATED NITRILES United States Patent 3574703 Abstract: 1,232,668. Production of α,#-unsaturated compounds. EASTMAN KODAK CO. 18 Oct., 1968 [23 Oct., 1967], No. 49515/68. Heading C2C. α,#-Unsaturated aldehydes, ketones, nitriles or carboxylic esters in which...
Irradiation of α-iodo ketone in hexane under a nitrogen atmosphere with a high-pressure mercury lamp (λ>300nm) at room temperature afforded the corresponding α,β-unsaturated ketones in good yield. This reaction affords a new, clean and convenient synthetic method for the α,β-unsaturated ke...
摘要: α,β-unsaturated ketones were obtained in hig h yields by grinding a mixture of aromatic aldehyde,2,3-dihydroinden-1-one (3,4-dihydronaphthalen-1(2H)-one) and NaOH at room temperature.It is a simple and efficient method to synthesize these compounds....
A facile synthesis of various substituted a,b-unsatd. ketones utilizing nitroalkenes and sulfones are described, in which conjugate addn. of sulfonyl carbanions to nitroalkenes, ozonolysis or acid treatment of the resulting lithium nitronates, and subsequent elimination of sulfinic acid from keto sulf...
A straightforward two-step entry to α-oxgenated β,γ-unsaturated ketones from readily available α,β-unsaturated ketones is disclosed. It was found that bis(allylic) alcohols undergo a skeletal rearrangement in the presence of 1 mol% of cheap and non-corrosive p-toluenesulfonic acid. Computatio...
Synthesis of (E)-α,β-unsaturated ketones with total or high diastereoselectivity by using samarium diiodide or triiodide (E)-α,β-Unsaturated ketones are obtained by reaction of α-chloro-β-hydroxy ketones with samarium diiodide or with samarium triiodide with total or high... JMC Huerta -...
Heating the alcohols in boiling toluene resulted in removal of pentamethylcyclopentadiene to provide β,γ-unsaturated ketones. The removal would proceed via a retro-carbonyl-ene process. Synthesis of an alkyl allyl ketone is also described.关键词: allylation cleavage pentamethylcyclopentadiene ketones ...
The deoxyfluorination reaction of β-diketones with N, N-diethyl-α,α-difluoro- m-methylbenzylamine (DFMBA) gave β-fluoro-α,β-unsaturated ketones in good yields. The reaction proceeded regioselectively, and only one regioisomer was obtained from the unsymmetrical 1-aryl-1,3-diketones. The...
Catalytic enantioselective peroxidation of alpha,beta-unsaturated ketones. Despite the potential of chiral peroxides as biologically interesting or even clinically important compounds, no catalytic enantioselective peroxidation ha... X Lu,Y Liu,B Sun,... - 《Journal of the American Chemical Society》 ...