Herein, acetylsalicylic acid was synthesized from the sulfuric acid-catalyzed reaction of salicylic acid and acetic anhydride on a laboratory scale. A mass of 2.55 g (0.0142 mol) a white, crystalline, solid product was successfully isolated, corresponding to a 64.5% yield. The identity and purity...
The effects of WO 3 concentration, reaction time, reaction temperature, molar ratio of reactants, as well as dosage of catalysts on synthesis of acetyl salicylic acid were investigated, and the reaction conditions were therefore optimized. The excellent yield (91.0%) of acetylsalicylic acid was ...
When the esterification reaction is complete, water will be added to the mixture. This will cause the precipitation of the acetylsalicylic acid and will react with any remaining acetic anhydride. The solid aspirin will be collected using vacuum filtration. Any other reaction ingredients that are solu...
Recently, Liu et al.12 synthesized a new derivative by the reaction of salicylic acid with α-aminophosphonate and demonstrated that the synthesized salicylic acid derivative had inhibitory activity against liver and cervical cancer cell lines. Salicylic acid is very sensitive to oxidation, as its...
Kolbe-Schmitt Synthesis is a chemical reaction used for the preparation of β-Resorcylic Acid by carboxylation of the aromatic nucleus. AI generated definition based on: Sourcebook of Advanced Organic Laboratory Preparations, 1992 About this pageSet alert ...
theacidcatalyticperformanceofthecatalyst,undertheoptimalcondition,i.e.thesupportedquantityof40%,w(catalyst)=7.2%(relativetothedosageofsalicylicacid),reactiontemperatureof90℃,andreactiontimeof40min.Theaverageyieldofacetylsalicylicacidreaches90.2%.Thecatalystshowsgoodreusability.Afteritsfivetimeusage,theyieldof...
SJ-101 exhibited more stronger activity to aspirin at collagen aggregation reaction. These finding demonstrates that SJ-101 is usefull as care drug of aging and old-disease because of its has antioxidant activity, anti-coagulant activity and anti-platelet activity. 展开 关键词:...
Development of a triple impinging jet mixer for continuous antisolvent crystallization of acetylsalicylic acid reaction mixture Chem. Eng. Process., 165 (2021), Article 108446, 10.1016/J.CEP.2021.108446 View PDFView articleView in ScopusGoogle Scholar [16] R. Baber, L. Mazzei, N.T.K. Thanh, ...
All NSAIDs, including acetylsalicylic acid, may induce hypersensitivity reactions, which are of two general types. Both may be related to the inhibition of PG synthesis. They are (1) the syndrome of asthmatic attacks in patients with vasomotor rhinitis, nasal polyposis, and bronchial asthma and ...
1. Study on the microwave synthesis of acetylsalicylic acid by p-Toluene Sulphonic Acid catalyst; 对甲苯磺酸催化微波合成乙酰水杨酸的研究2. Water-bath microwave synthesis of hydrophobic imidazolium-based ionic liquids; 疏水性咪唑类离子液体的水浴微波合成...