In intelligence usage, the examining and combining of processed information with other information and intelligence for final interpretation. Dictionary of Military and Associated Terms. US Department of Defense 2005. synthesis 1.the process of putting two or more things, concepts, elements, etc., tog...
The compounds with the halogen atoms in the aromatic ring, and N,N-diethylamino or N,N-dimethylamino groups in the side chains at C-3 positions exhibited good inhibitory activity. SAR study was carried out by means of molecular docking technique. According to molecular docking results, the ...
Which compound classes are best suited as probes and tools for chemical biology research and as inspiration for medicinal chemistry programs? Chemical space is enormously large and cannot be exploited conclusively by means of synthesis efforts. Methods are required that allow one to identify and map ...
Antibiotic resistances are used differently than other genes. Notably, the requirement of every plasmid to contain an antibiotic resistance or other selective marker means that a small number of genes are used highly redundantly. In addition, antibiotic resistances have been acquired by natural pathogens...
- 《Chemistry & Biology》 被引量: 252发表: 2003年 Biochemical properties of regulatory peptides derived from milk proteins. Biologically active peptides derived from milk proteins are inactive within the sequence of the precursor proteins but can be released by enzymatic proteol... H Meisel - 《...
CURRENT OPINION IN BIOTECHNOLOGYKopp, F., Marahiel, M.A. (2007). Where chemistry meets biology: The chemoenzymatic synthesis of nonribosomal peptides and polyketides. Current Opinion in Biotechnology, 18, 513-520.Kopp, F,Marahiel, M.A.Where chemistry meets biology: the chemoenzymatic synthesis ...
Synthetic biology confers new functions to hosts by introducing exogenous genetic elements, yet rebuilding complex traits that are based on large-scale genetic information remains challenging. Here, we developed a CRISPR/Cas9-mediated haploidization method that bypasses the natural process of meiosis. Bas...
Oxidation reactions are among the most elementary of organic transformations and are essential in biology, chemical industry and (synthetic organic) chemistry. Selective oxidation of hydrocarbons, such as cis-dihydroxylation and epoxidat... Boer,JW De 被引量: 16发表: 2008年 Synthesis, Characterization...
The firstamino acidsynthesis was reported in 1850 with the name ofStrecker synthesis. According to this reaction the conversion of an aldehyde or ketone and amine or ammonia to α-amino acids can be achieved by means of an acid catalysts, metal cyanide and water (Strecker, 1850). In particul...
Multiple super-resolution imaging techniques have become routine experimental tools and are now driving fundamental knowledge of molecular biology2,3. The transition from standard imaging of fixed samples towards living specimens in super-resolution microscopy is empowered by the discovery of compatible and...