SynergyFinder 利用最近开发的机器学习模型,基于复合非负矩阵分解 (cNMF) 算法 ( 10.1038/ s42256-019-0122-4 ). 默认情况下,“检测离群值”选项处于打开状态以允许自动识别离群值。 当检测到异常值时,SynergyFinder 会显示以下警告,作为检测到异常值的药物组合和药物剂量(括号内)的指示。 为了删除离群值测量,请...
SynergyFinder利用了多种数学模型和算法来预测和评估药物组合的协同效应。 组合索引 SynergyFinder使用组合索引来评估药物组合的效应。组合索引基于剂量-效应曲线,通过计算不同药物组合的组合效应指数来量化其协同效应。组合效应指数表达了组合药物与单药疗效之间的差异。 Loewe模型 SynergyFinder基于Loewe模型进行组合效应的计算...
add synergyfinder Sep 27, 2016 .travis.yml only keep bioconductor in .travis.yml Jan 29, 2018 DESCRIPTION fixes for missing concentration units merging from branch RELEASE_3_6 Feb 6, 2018 LICENSE change license to Mozilla Public License 2.0 ...
As the SynergyFinder R package provides four synergy models (i.e., HSA, BLISS, LOEWE, and ZIP) that differ in their null hypotheses of non-interaction, the synergy scores do not necessarily coincide with each other for a given dataset. To provide a more harmonized representation of the syne...
SynergyFinder数据分析网站 SynergyFinder数据分析网站又可以进去了!!! SynergyFinder - Documentatio
synergyfinder 2460_ visual analytics of multi-drug combination synergies462020nucleic acids res 系统标签: drug nucleic synergies combination analytics acids NucleicAcidsResearch,20201doi:10.1093/nar/gkaa216SynergyFinder2.0:visualanalyticsofmulti-drugcombinationsynergiesAleksandrIanevski1,2,*,AnilK.Giri1,*and...
sunnivas/synergyfinderPublic NotificationsYou must be signed in to change notification settings Fork1 Star0 Folders and files Name Last commit message Last commit date parent directory .. CITATION version 0.99.1 Jun 20, 2016 NEWS Typos in NEWS file ...
50, Web Server issue W739–W743https://doi.org/10.1093/nar/gkac382SynergyFinder 3.0: an interactive analysis andconsensus interpretation of multi-drug synergiesacross multiple samplesAleksandr Ianevski 1,2,* , Anil K. Giri 1,3,* and Tero Aittokallio1,2,4,5,*1 Institute for Molecular ...
Ianevski A, He L, Aittokallio T and Tang J: SynergyFinder: A web application for analyzing drug combination dose-response matrix data. Bioinformatics 33: 2413-2415, 2017.Ianevski A, He L, Aittokallio T, Tang J. SynergyFinder: a web application for analyzing drug combination dose-response ...
SynergyFinder (https://synergyfinder.fimm.fi) is a free web-application for interactive analysis and visualization of multi-drug combination response data. Since its first release in 2017, SynergyFinder has become a popular tool for multi-dose combination data analytics, partly because the developmen...