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There is a dire need for new classes of antibiotics with novel mechanisms of action (MOA), for which there are currently few options. Antibiotic resistance, especially among Gram-negative bacteria, is rising rapidly, and the World Health Organization considers the development of novel targets to c...
Starting with the Solidigm Synergy Driver, this feature will automatically improve the performance of Solidigm SSDs by delivering the latest firmware and driver updates to your SSD. It enhances user experience by closing the gap between PC and SSD, automatically optimizing per...
glycolysis/gluconeogenesis (IbGAPC,IbPKc, andIbPKp), and starch biosynthesis (IbAGPL,IbAGPS,IbGBSS,IbPTST,IbSSII, andIbSBEI) were generally more highly expressed in H283 than in L423 (Fig.4cand Supplementary Datas10,11). These genes were referred to as source-sink related genes. ...
Perio Master Clinic is a triennial, hands-on conference which aims to upskill and update the technique and practical mastery of dental practitioners, so that they can take better care of their patients’ oral health but also so that they can treat the sequelae of periodontitis efficiently...
The World Health Organization has identified antimicrobial resis- tance as one of the three most important problems affecting human health and carbapenem-resistant A. baumannii as a critical priority pathogen to help in prioritizing the research and development of new and effective antibiotic treatments....
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They also agreed upon a mission: to provide unique, affordable services using collaborative, innovative approaches for the benefit of the entire healthcare continuum with a focus on improving efficiencies and health out comes in rehabilitation and clinical services, critical...
Subsequently, the cells were observed for 18 h by time-lapse microscopy at 37 °C and 5% CO2 using a DeltaVision ELITE microscope (GE Healthcare, NW, USA). Image stacks were recorded every 5 min using a PCO Edge sCMOS camera (PCO, Stuttgart, Germany) with a Z-optical spacing of 4 ...
PANC-1 pancreatic adenocarcinoma cells have only one allele of TP53, which contains an R273C mutation in the DNA-binding region; HeLa cervical adenocarcinoma cells have wild-type TP53 but no functional p53 protein due to rapid degradation; and PC-3 prostate adenocarcinoma cells have both TP53 al...