Conceptually,DICER1can be regarded as either a tumor suppressor gene due to loss-of-function mutations or an oncogene due to gain-of-function mutations; it is thought to function as a haploinsufficient tumor suppressor gene with the loss of one allele leading to tumor progression but loss of ...
Recurrent ovarian Sertoli-Leydig cell tumor in a child with Peutz-Jeghers syndrome. Oxford Med. 2016, 2016. [CrossRef] [PubMed] 62. Durieux, E.; Descotes, F.; Mauduit, C.; Decaussin, M.; Guyetant, S.; Devouassoux-Shisheboran, M. The co-occurrence of an ovarian Sertoli-Leydig ...