Synaptotagmin 1 (Syt1) is a Ca2+ sensor in the membrane of pre-synaptic axon terminal, which functions as an essential regulator of neurotransmitter release and hormone secretion and plays an important role in learning, memory and thinking. The sevoflurane, a general anaesthetics used widely in ...
Synaptotagmin 1ligand-binding siteanaestheticscognitionsevoflurane(2016). Structure-based exploration of sevoflurane binding sites in cognition-related synaptotagmin-1. Molecular Simulation: Vol. 42, No. 12, pp. 948-954. doi: 10.1080/08927022.2015.1124104...
Chen GH, Wang YJ, Qin S, Yang QG, Zhou JN, Liu RY. Age-related spatial cognitive impairment is correlated with increase of synaptotagmin 1 in dorsal hippocampus in SAMP8 mice. Neurobiol Aging. 2007;28(4):611-8.Chen GH,Wang YJ,Qin S et al.Age-related spatial cognitive impairment is ...