In this study, synaptic vesicle glycoprotein 2 A (SV2A) was examined to improve the early diagnostic efficiency in AD. Methods: In this study, biomarker testing was performed through the single-molecule array (Simoa). A total of 121 subjects including cognitively unimpaired con...
英文名称:Synaptic Vesicle Glycoprotein 2A (SV2A) Antibody (HRP),中文名称:突触囊泡糖蛋白2A(SV2A)抗体(HRP),产品货号:Catalogue No: abx337850,SV2A抗体(HRP)是一种针对SV2A的兔多克隆抗体。靶SV2A反应性人宿主兔克隆性多克隆试
The synaptic vesicle glycoprotein SV2A belongs to the major facilitator superfamily (MFS) of transporters and is an integral constituent of synaptic vesicle membranes. SV2A has been demonstrated to be involved in vesicle trafficking and exocytosis, processes crucial for neurotransmission. The anti-seizure...
8,9. Genetic studies have found associations between schizophrenia and variants in genes encoding synaptic proteins10,11. A polymorphism in the synaptic vesicle glycoprotein 2A gene (SV2A) has been associated with increased schizophrenia risk12, although this finding has not been replicated...
et al. Assessing synaptic density in Alzheimer disease with synaptic vesicle glycoprotein 2A positron emission tomographic imaging. JAMA Neurol. 75, 1215–1224 (2018). Article Google Scholar Mecca, A. P. et al. Association of entorhinal cortical tau deposition and hippocampal synaptic density in ...
Synaptic vesicle glycoprotein 2A (SV2A) has been previously characterized as an imaging biomarker for assessment of synaptic density in positron emission tomography (PET) studies of patients with neurological conditions. To provide detailed maps of the brain localization of SV2A autoradiography studies we...
Synaptic vesicleglycoprotein 2 (SV2) occurs in two main isoforms in the brain, SV2A and SV2B. This protein can bind twoadeninemolecules and possibly links cellular energy state to vesicle release. Mice engineered to lack both SV2 isoforms possess a smaller number of readily releasable SVs, whi...
Synaptic vesicle protein 2 (SV2) is a glycoprotein identified in the nervous system of several species, including man, but its occurrence in the human neuroendocrine (NE) cell system has not been investigated. By using a monoclonal antibody to SV2, immunoreactivities were demonstrated in NE ...
The synaptic vesicle glycoprotein 2: structure, function, and disease relevance ACS Chem. Neurosci., 10 (9) (2019), pp. 3927-3938 CrossrefView in ScopusGoogle Scholar [55] A.M. Butt, A. Kalsi Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for...
Among validated CELF4-targets is the mRNA encoding the synaptic vesicle glycoprotein 2 A (SV2A). SV2A is highly expressed in all glutamatergic and GABAergic cortical subtypes, both of which are also present in the developing SP4,5,6,7,9,10,11,12,13,14,17. Recent studies have identifie...