Dissociated hippocampal cultures labeled for GluR2. (A) (a and b) denote a spine and a shaft synapse, respectively. Neurites in dissociated cultures are not compactly organized, and there is a lot of extracellular space (∗) among processes. (B) A longitudinal section through a dendritic ...
bipolar cell ribbon synapses in mouse and bovine retina but do not label these synapses in goldfish and salamander retina, which are instead labeled by antibodies to synaptotagmin III. In hair cells, it has been proposed that otoferlin, not synaptotagmin, is the principal calcium sensor for ...
Fig. 1: Exposure to p4.2 induces a biphasic response in synaptic strength. Full size image Fig. 2: Rapid synapse formation compensates synaptic elimination caused by p4.2. Full size image Increased presynaptic calcium influx compensates synapse loss ...
ARepresentative images of RNAscope in situ hybridization forApoemRNA (red) expression in Cx3cr1-positive microglia (green), with nuclei labeled with DAPI (blue). Scale bar 20 µm.BQuantitation ofApoemRNA per DAPI nucleus in layer 2 mPFC of wildtype and C3−/−control/CORT mice, no...
Synaptic inhibition controls a neuron's output via functionally distinct inputs at two subcellular compartments, the cell body and the dendrites. It is unclear whether the assembly of these distinct inhibitory inputs can be regulated independently by neurotransmission. In the mammalian retina, γ-amino...
In an additional monkey, a lamina I cell retrogradely labeled from the ventral posterolateral nucleus of the thalamus was found to be ensheathed in glial processes.(ABSTRACT TRUNCATED AT 250 WORDS) 展开 关键词: excitatory amino acid gamma‐aminobutyric acid spinal cord pain ultrastructure colloidal ...
Time-lapse confocal microscopy of individual, double-labeled neurons revealed a coincident, activity-dependent mechanism of synaptogenesis and axon and dendritic arbor growth, which is differentially modulated by BDNF. Microinjection of BDNF into the optic tectum significantly increased synapse number in ...
This is a fluorescence image of a neuron labeled for synapses (green) and cell structure (magenta). Credit: Yoichi Araki Researchers at Johns Hopkins say they have found that a gene already implicated in human speech disorders and epilepsy is also needed for vocalizations and synapse formation ...
a member of the L1CAM family that is expressed by axons of stellate cells and by Bergmann glia, perturbed arborization and terminal formation of stellate cell axons, reduced their synaptic contacts with PCs, and led to age-dependent axonal degeneration [55]. A study on fluorescently labeled ...
The most common site of synaptic contact on a neuron is on the dendrites or dendritic spines. These types ofsynapsesare referred to as axodendritic or axospinous. In cells that possess dendritic spines, the vast majority of synapses occur onto the spine heads, whereas few synapses are observed...