Sydney Brenner开创了一个时代:建立秀丽隐杆线虫Caenorhabditis elegans为模式生物来系统研究多细胞复杂生物体发育及其它重要生物学过程。2019年4月5日,Brenner去世,享年92岁。我们来回忆Brenner几个特别重要的时刻,以飨读者。 2000年,Brenner在伯克利的分子科学研究所观察细菌克隆生长状况,该研究所于1996年由Brenner发起成立。
Sydney Brenner开创了一个时代:建立秀丽隐杆线虫Caenorhabditis elegans为模式生物来系统研究多细胞复杂生物体发育及其它重要生物学过程。2019年4月5日,Brenner去世,享年92岁。我们来回忆Brenner几个特别重要的时刻,以飨读者。 2000年,Brenner在伯克利的分子科学...
作者: 转:20 世纪 60 年代,多才多艺的剑桥大学科学家悉尼-布伦纳(Sydney Brenner)为破译遗传密码做出了贡献--遗传密码是一种机制,规定了基因的 DNA 序列如何被翻译成蛋白质的氨基酸序列。20 世纪 70 年代,布伦纳开始定义另一种密码:决定单细胞内的基因如何勾勒出多细胞生物体三维组织的生物生成规则。"他在一篇关...
5. Brenner, S. The Genetics of Caenorhabditis elegans GENETICS May 1, 1974 77: 71–94 6. ...
His selection of Caenorhabditis elegans was so well thought out that it allowed him not only to perform lineage analysis for each of the 959 cells but also let White and Brenner draw the entire wiring diagram for the nervous system of C. elegans, a feat not accomplished for any other ...
programmed cell deatheliminates 131 cells inC. elegans, so that adults wind up with 959 body cells. Brenner’s investigations showed that achemical compoundcouldinducegenetic mutations in the worm and that the mutations had specific effects on organ development. His work laid the foundation for ...
Sydney Brenner. Self: Imagined Worlds. Sydney Brenner was born on 13 January 1927 in Germiston, Gauteng, South Africa. He was married to May Covitz Balkind. He died on 5 April 2019 in Singapore.
Friedberg has come to Brenner relatively late and in... B Bridges - 《Dna Repair》 被引量: 68发表: 2010年 Sydney Brenner on the Genetics of Caenorhabditis elegans BRENNER, Sydney, 1927-2019Sydney Brenner decided on his lifelong scientific goals on one cold day in April 1953. He was a.....
The complete structure of the anterior sensory nervous system of the small nematode C. elegans has been determined by reconstruction from serial section el... S Ward,N Thomson,JG White,... - 《Journal of Comparative Neurology》 被引量: 1302发表: 1975年 E.C. Friedberg, Sydney Brenner—A Bi...
找到了梦寐以求的生物之后,Sydney Brenner组织了一支特殊的队伍来开启线虫计划(C. elegans project)。这支队伍中,大家背景各异,并不全是生物学家。 John Sulston,有机化学家,研制出一种特定的溶液将线虫长期保存在零下80度,随时可以复苏。Robert Horvitz,数学家,和John Sulston一起探明了线虫完整的细胞谱系[7]。