simian virus(SV40 T antigen)immortalizationinsight into wild‐type function of pathwaysSummary This chapter contains sections titled: Introduction Immortalization SV40 Large T Antigen The Retinoblastoma Family of Proteins The P53 Protein The J Domain and H sc 70 p300 and the CBP Family of Proteins ...
## SV40 Large T Antigen: Structure and Function. Simian virus 40 (SV40) large T antigen (TAg) is a multifunctional protein that plays a critical role in viral replication, regulation of host gene expression, and immortalization of primary cells. The structure of TAg has been extensively studied...
Immortalization Method:Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen Applications:For Research Use Only Unit quantity:1x10^6cells/ 1.0 ml Cell Type:Immortalized Cells Propagation Requirements:Use of PriCoatTMT25 Flasks (G299) or Applied Cell Extracellular M...
Immortalization Method :Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen Applications :For Research Use Only Unit quantity:1x1066 cells / 1.0 ml Cell Type :Immortalized Cells Propagation Requirements:Use of PriCoatTMT25 Flasks (G299) or Applied Cell Extracel...
Immortalization Method Serial passaging and transduction with recombinant adenovirus carrying SV40 Large T antigen Description The Immortalized Lens Epithelial Cells - SV40 is established from primary cells (isolated from infant lens epithelial fragments) using adenovirus-SV40 virus. The Immortalized Human Len...
Shay JW, Van Der Haegen BA, Ying Y, Wright, WE (1993) The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen. Exp Cell Res 209: 45–52.Shay JW, Van Der Haegen BA, Ying Y, Wright WE. The frequency of immortalization of ...
Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts 来自 NCBI 喜欢 0 阅读量: 51 作者:LM Crosby,TM Moore,M George,LW Yoon,AB Deangelo 摘要: Background Simian Virus 40 (SV40) immortalization followed by ...
7 Miyazaki M, Mihara K, Bai L et al. Immortalization of epithelial-like cells from human liver tissue with SV40 T-antigen gene. Exp Cell Res, 1993;206(1):27-35 8 吴根生, 陈秋燕, 孙宗棠 et al. SV40 T抗原介导的人胚肝细胞的体外永生化及其机制探讨. 中华肿瘤杂志, 1993;15(6):415-418...
内容提示: SV40 大 T 抗原对人皮肤成纤维细胞生物学行为的影响 作者: 王新文, 金岩, 刘源, 王军琳,赵宇, 董蕊 【关键词】 大 T 抗原 【Abstract】 AIM: To investigate the role of SV40 large T (LT) antigen on human skin fibroblasts transformation and to observe the biological alteration of the ...
Immortalization MethodTransfection with pSV-3 plasmid with the SV40 large T antigen DescriptionImmortalized MHC II -/- Mouse Macrophage Cells (C2Dt) is derived from the knockout mice negative for MHCII molecule. Unlike the Immortalized MHC II -/- Mouse Macrophage Cells (C2D) (abm, T0225), C2...