The most recent guidelines, published in 2013, provide detailed management strategies for acute care, fluid resuscitation, and vasopressor use. In addition, the campaign has developed simple, short protocols for what to do within 3 and 6 hours of recognition of sepsis. These pro...
To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ dysfunction. Design A panel of 49 international experts, representing 12 international organizations, as well as three...
The most recent SSC guidelines (2016) were sponsored by 35 international professional medical societies and have emerged as the global standard for sepsis management such that some randomized clinical trials now use the SSC guidelines to standardize sepsis care across the control and intervention groups...
A recent systematic review of 9 RCTs (n = 637 patients) comparing restricted versus liberal fluid volumes in the initial resuscitation of patients with sepsis found no statistically significant difference in mortality (RR 0.87, 95% CI 0.69–1.10) and serious adverse events (RR 0.91, 95% C...
Septic encephalopathy is frequent but its pathophysiology is enigmatic. We studied expression of neurotransmitters, inflammation and integrity of the blood–brain barrier (BBB) in several brain regions during abdominal sepsis. We compared mice with eithe
(Those waxing-and-waning symptoms turned out to be sepsis. Yikes.) Even so, it’s always fun to meet someone who’s been commenting on your stuff – especially since Ro has been a commenter since my MSN Money days. She always had (and has) thoughtful things to say. Read more ...
Continued efforts to address potentially modifiable factors during the neonatal period, including sepsis and postnatal corticosteroid use, are critical. Of note, BPD was most strongly associated with high-service use, with a greater than 2-fold increase in the odds of using more than 5 SOS. This...
One of the most vexing questions facing forestry today is whether sustainable forestry is possible in natural forests. In this publication past forest mana... N Johnson,B Cabarle - 《Washington D》 被引量: 157发表: 1993年 The Surviving Sepsis Campaign: past, present and future The Surviving...
Specifically, we chose several most commonly used parameters characterizing selected aspects of cellular injury and/or function of vital organs and compared them among CLP mice either dying or surviving the acute phase of sepsis and surviving septic animals with added organ damage....
However, sepsis and kidney failure had a higher impact on the ICU LOS (+7.8 days and +8.1 days, respectively). Overall, there was a trend of reduced LOS in the ICU in recent years (treated from the year 2007: -1.3 days). The remaining parameters (gender, age 16 to 49 years, AIS ...