Department of Medical OncologyM.Department of Medical OncologyBlacksteinDepartment of Medical OncologyAnnals of OncologyAljubran AH, Griffin A, Pintilie M, Blackstein M. Osteosarcoma in adolescents and adults: survival analysis with and without lung metas- tases. Ann Oncol. 2009;20(6):1136-1141....
Three patients developed a second malignancy (one fatal) after 300 months. Conclusion Though the primary endpoint of OSAD93 was not met, this pre-operative doxorubicin-free regimen led to excellent long-term survival with limited toxicity in localized osteosarcoma....
Therefore, in the current study, we built an AI classifier by using the XGBoost algorithm to predict the 5-year survival of osteosarcoma patients, and aimed to construct a better AI prediction model. We extracted the samples from the SEER program database to train and cross-validate our predic...
Another cadherin implicated as a metastasis suppressor is N-cadherin, which when overexpressed in the LM8 osteosarcoma line, inhibited pulmonary metastasis (Kashima et al., 2003). However, there are contradictory data showing that N-cadherin can increase aggressiveness and metastasis in breast ...
Patterns of care and survival for patients aged under 40 years with bone sarcoma in Britain, 1980-1994 The purpose of the study was to calculate population-based survival rates for osteosarcoma (OS) and Ewing's sarcoma (ES) in Great Britain during 1980-1994,... CA Stiller,SJ Passmore,PA ...
To assess outcome and identify predictors of survival of adults with rhabdomyosarcoma.The literature on adult rhabdomyosarcoma is limited. Few studies have identified predictors of long-term survival in this patient population.Thirty-nine adults with rhabdomyosarcoma were treated between 1973 and 1996 and...
Patients diagnosed with advanced osteosarcoma, often in the form of lung metastases, have abysmal five-year overall survival rates. The complexity of the osteosarcoma immune tumor microenvironment has been implicated in clinical trial failures of various immunotherapies. The purpose of this exploratory stu...
Imatinib is highly effective in the treatment of chronic myelogenous leukemia (CML), but the primary and acquired imatinib resistance remains the big hurdle. Molecular mechanisms for CML resistance to tyrosine kinase inhibitors, beyond point mutations in
The aim of treating childhood cancer remains to cure all. As survival rates improve, long-term health outcomes increasingly define quality of care. The International Childhood Cancer Outcome Project developed a set of core outcomes for most types of chil
The calculation of an expected survival (based on some reference population) for a cohort of patients under study has a long history. These methods are most familiar when the reference population is census based, for example, the overall survival experience of the United States population by age...