Survival of HER2-positive primary breast cancer patients treated by neoadjuvant chemotherapy plus trastuzumab: a multicen- ter retrospective observational study (JBCRG-C03 study). Breast Cancer Res Treat. 2014;145:143-53.Takada M, Ishiguro H, Nagai S et al (2014) Survival of HER2- positive ...
Median overall survival since initial diagnosis of metastasis was 34 months (0-277+). Conclusion: It could be shown that, compared to historical controls, targeted therapy against HER2 prolongs overall survival of patients with HER2-positive metastatic breast cancer who receive treatment in routine ...
Trastuzumab for patients with HER2 positive breast cancer: Delivery, duration and combination therapies With the exception of endocrine therapy, no other systemic treatment of patients with breast cancer has reached such a magnitude of beneficial effect as tr... AC Pinto,F Ades,AE De,... - 《...
The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells — A data description Perala, O. Kallioniemi, The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells. Mol. Oncol. ... ...
Kaplan–Meier curves for HER2 status. Survival curves showing cumulative survival differences (end point=breast cancer-specific survival) between patients positive or negative for HER2. P-value represents log-rank testing of the difference in cumulative survival. Full size image Table 2 Subgroup hazard...
Intratumoral human epidermal growth factor receptor 2 (HER2) heterogeneity has been reported in 16–36% of HER2-positive breast cancer and its clinical impact is under discussion. We examined the biological effects of HER2-heterogeneity on mouse models and analyzed metastatic brains by RNA sequence ...
Patients who completed 12 months of trastuzumab had a 9-year OS rate of 90.2% compared with 86.2% among patients receiving <12 months of therapy (adjusted HR 0.71, 95% CI 0.62–0.81).Real-world HER2 + EBC patients are less likely to complete 12 months of trastuzumab than some ...
relative survival rate than those ages 50 and up. Younger people AFAB are less likely to be diagnosed at an early stage compared to older people. They’re also less likely than older people to have hormone-receptor-positive breast cancer, which meanshormone treatmentisn’t a good option for ...
Significant survival impact of \\{MACC1\\} polymorphisms in \\{HER2\\} positive breast cancer patients Geller-Rhomberg S, Gasser K, Winder T, Drexel H, et al .: Significant survival impact of MACC1 polymorphisms in HER2 positive breast cancer patients. ... Axel,Muendlein,Michael,... -...
Breast Cancer Survival Rates Relative Breast Cancer Survival Rate by Stage Relative Breast Cancer Survival Rate by Age 11 min read If you’ve been diagnosed with breast cancer, your focus will be on getting the right treatment, but you’ll wonder, too, about your chances of surviving. Your...