Dual-targeted therapy plus chemo boosts response rate in BRAF-mutated metastatic colorectal cancer Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefited from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen...
Within the scan, the Mann-Whitney rank sum test quantified the length and diameter of air emboli situated along the inflow trajectory of the contrast agent.The control group had an occurrence rate of 1055%, in contrast to the 374% occurrence rate in the case group; the difference was ...
A common survival analysis technique is Cox proportional hazards regression (Cox 1972) which models the hazard rate for an event as a linear combination of covariate effects. Although this model is widely used and easily interpreted, its parametric nature makes it unable to identify non-linear effe...
The average rate of cognitive decline in the 81 mild to moderate demented subjects who survived 3 years was 2.4 MMSE points per year. Type of dementia... H Agüero-Torres,L Fratiglioni,Z Guo,... - 《Journal of the American Geriatrics Society》 被引量: 470发表: 1998年 Life-Years Gaine...
The survival rate of children receiving treat-and-repair was slightly higher than that of ES (= 0.16). The independent mortality risk in children with PAH-CHD-predominantly L-R shunt was persistent PAH following the defect correction (adjusted hazard ratio 5.8, 95% CI 1.7–19.9,= 0.005)....
Although evidence-based treatment has reduced the mortality of CHF, the mortality in severe cases still approaches 50%, even worse than the prognosis of the common cancers [2]. Therefore, seeking an effective approach to improving the survival rate of CHF has become an urgent medical challenge ...
(Penedo and Dahn2005), and improvements in survival among people of all ages (Löllgen et al.2009). Current public health policies rate physical activity together with diet as the most critical issues in health promotion, especially in light of the increasing prevalence of obesity and diabetes...
However, a longitudinal follow-up study on survival in the same sample indicated that 192RR homozygotes have a poorer survival compared to QQ homozygotes (hazard rate: 1.38,=0.04). We hereafter used an independent sample of 541 Danish individuals from the oldest cohort and confirmed the initial...
Higher fitness, but not a lower number of risk factors, was associated with improved survival, the researchers wrote. In an adjusted Cox model, older adults with three or more risk factors with moderate fitness had reduced mortality rate (mortality...
The higher rate of survival into adulthood post-Fontan procedure is a likely factor as a result of improved management of single ventricle anatomy. Post... Candida,Pinto,J Joseph,... - 《World Journal for Pediatric & Congenital Heart Surgery》 被引量: 3发表: 2015年 Catheter ablation of atri...