此外,计划进行评估该药物的II期研究,包括正在招募的食管和食管胃交界处癌患者(SURPASS-2;NCT04752358)和卵巢癌患者(SURPASS-3)。 参考文献: [1] Hong D , Clarke J , Johanns T , et al. 379 Initial safety, efficacy, and...
OBJECTIVE To assess the efficacy and safety of tirzepatide added to insulin glargine in patients with type 2 diabetes with inadequate glycemic control. DESIGN, SETTING, AND PARTICIPANTS Randomized phase 3 clinical trial conducted at 45medical research centers and hospitals in 8 countries (enrollment f...
(surpass intracranialaneurysmembolization systempivotaltrialtotreatlarge orgiantwideneckaneurysms, scent)[9]与tubridge血流导向装置治疗颅内动脉瘤的临床试验(intracranialaneurysmsmanaged byparentarteryreconstruction usingtubridgeflowdiverterstudy, impact)[18];在选择支架型号时,需根据动脉瘤情况选择支架直径及长度,具体...
SCENT研究(Surpass Intracranial Aneurysm Embolization System Pivotal Trial to Treat Large or Giant Wide Neck Aneurysms)是一项多中心、前瞻性、单臂、非随机的临床试验,主要用于弹簧圈难以栓塞的或治疗失败的动脉瘤,其纳入标准为:1)瘤颈≥4mm ...
support our belief that this is a highly active product,” said Ad Rawcliffe, Adaptimmune’s Chief Executive Officer. “Based on these data, we will initiate the Phase 2 trial in gastroesophageal cancers in the first half of 2021 ...
当前,血管内治疗已经成为颅内动脉瘤的主要治疗方式,其安全性和有效性已经被国际颅内未破裂动脉瘤研究(International Study of Unruptured Intracranial Aneurysms, ISUIA) [ 1 ]和国际蛛网膜下腔出血动脉瘤试验(International Subarachnoid Aneurysm Trial, ISAT) [ 2 ]等大型临床研究所证实。然而,传统的弹簧圈栓塞、颅...
New phase 1 SURPASS trial cohort: Early-line ADP-A2M4CD8 T-cell receptor T-cell therapy plus pembrolizumab in urothelial carcinoma.doi:10.1200/JCO.2024.42.4_suppl.TPS708211TPS708#Background:ADP-A2M4CD8 T-cell receptor (TCR) T-cell therapy consists of autologous CD4+ and CD8+ T-cells ...
tumors who have generally received extensive prior therapies. Based on clear efficacy signals thus far in the Phase 1 SURPASS trial, we are eager to now focus on the head & neck and bladder cancer cohorts i...
在接受基础胰岛素治疗的2型糖尿病患者中,与餐前胰岛素相比,作为甘精胰岛素的额外治疗,每周替西帕肽可降低糖化血红蛋白和体重,低血糖更少。 Trial Registration ClinicalTrials.gov Identifier: NCT04537923 ClinicalTrials.gov标识符:NCT04537923 ...
April 2, 2025 Trump’s Executive Orders On Trial Several of Trump's executive orders are facing legal challenges. Here’s where things stand now. Cecelia Smith-SchoenwalderApril 11, 2025 Trump’s Under-the-Radar Executive Orders Data privacy, Public Service Loan Forgiveness, offsho...