aSuppressing the immune system via anti-inflammatory treatments such as TNF-α inhibitors can lead to unwanted dampening of the immune response, weakening its ability to respond to infection. IL-22 is an ideal therapeutic candidate because it specifically affects tissue responses and does not have ...
Suppressing the Immune SystemThe article states that transplant recipients must take drugs to suppress the immune system for the rest of their lives.Odyssey
Medicament useful for suppressing the immune system, treating necrotic cell death, ischemia, hypoxia, trauma, diabetes mellitus, myocardial infarction and/or cerebral ischemia, and treating the patients after resustication 机译:用于抑制免疫系统,治疗坏死细胞死亡,局部缺血,缺氧,外伤,糖尿病,心肌梗塞和/或...
immune systemorgan transplantationtransplanted organLink to PDF of JAMA Patient Page.doi:10.1001/jama.283.18.2484transplanted organAmerican Medical AssociationThe Journal of the American Medical Association
Our immune system is vital as a protective mechanism against foreign agents, including viruses and bacteria. However, an exaggerated immune response can have damaging effects on thebody, as is the case in autoimmune diseases, for example. The regulation of this system is thus important. ...
Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections. These viruses remain a serious health threat, but researchers from the University of Missouri School of Medicine have discovered how an enzyme that regulates several cellular processes...
The current status and future directions of myxoma virus, a master in immune evasion p pMyxoma virus (MYXV) gained importance throughout the twentieth century because of the use of the highly virulent Standard Laboratory Strain (SLS) by the... B Spiesschaert,G Mcfadden,K Hermans,... - 《...
In particular, DGG-100629 suppressed the nuclear translocation of NFATc1 through JNK activation, resulting in inhibition of DDIAS expression and STAT3 signaling. These findings suggest that NFATc1 functionally links the immune system to DDIAS and STAT3-mediated oncogenic signaling, which in turn ...
The application of Ami, an NHE1 inhibitor in the CUMS model, further indicated the clinical promise of NHE1 inhibition in the treatment of depression. Of note, LPS injection challenged the immune system, resulting in neuroinflammation, which is closely associated with neuronal apoptosis in the ...
Abundant evidence has shown that tumor-resident bacteria could regulate the host immune system through microbial metabolites [26,27,28]. To further investigate the effects of S. multivorum on the TME, targeted metabolomics analysis was performed in tumor tissues from the 4T1 tumor-bearing mouse mo...