Full size table A computerized algorithm called “Rank Ordering of Super-Enhancers” (ROSE) was developed to predict SEs based on ChIP-seq signal in 2013 [6]. This algorithm stitches together enhancers located within a certain distance (<12.5 kb) and ranks all stitched enhancers based on their...
transcription, and enhancer-promoter interactions. Facilitators are interchangeable but exhibit functional hierarchy based on their position within a multipartite enhancer. It is worth mentioning that diverse SE regulates a single target gene in different cell types [58]. Transcriptional dysregulation of the...
The algorithm is correct but inefficient. Consider what happens when"aa"is successfully matched, but'b'is not. The algorithm will start matching"aab"once again from the second character ofs, although it can already be said that the second character ofsis'a'. The deterministic finite automaton ...
Dissecting super-enhancer hierarchy based on chromatin interactions. Nat. Commun. 9, 943 (2018). Article ADS PubMed PubMed Central Google Scholar Kempfer, R. & Pombo, A. Methods for mapping 3D chromosome architecture. Nat. Rev. Genet. 21, 207–226 (2020). Article CAS PubMed Google ...
stitching enhancers and ranking the stitched enhancers through their ChIP-seq signals in the genomic region via the rank ordering of super-enhancers (ROSE) algorithm; and step 3, separating SEs from typical enhancers based on a cutoff value using the ROSE algorithm, which takes into account enhanc...
Can a biologically-plausible hierarchy effectively replace face detection, alignment, and recognition pipelines? .[J] arXiv preprint arXiv:1311.04082. P. Kiran Sree, I. Ramesh Babu .Face Detection from still and Video Images using Unsupervised Cellular Automata with K means clustering algorithm .[J...
cell lines were connected if their SE associations are statistically significant (Benjamini–Hochberg (BH)-adjustedP < 0.001). Furthermore, MCL (Markov cluster algorithm) was employed to identify enriched modules of cell lines in the association network with the default parameter setting26,27. ...
while the main disadvantages include the lack of a predefined sensitivity ranking for biological and human-use resources and the need for expert interpretation to define areas of prioritized protection. Algorithm-based sensitivity models facilitate the generation of a single computed value that corresponds...
Additionally, the built-in hierarchical allocator can be extended without the need to reimplement the entirety of the allocation logic. This is possible through the use of theSorterabstraction. Sorters define the order in which hierarchy layers (e.g. roles or frameworks) should be offered resource...
You might have used other HTML code cleaners, but this one’s powered by the HTML Tidy algorithm so you get accurate validation results. Key Highlights: Real-time error detection. Validation against multiple HTML standards. Integration with other developer tools. ...