求翻译:Sumoylated是什么意思?待解决 悬赏分:1 - 离问题结束还有 Sumoylated问题补充:匿名 2013-05-23 12:21:38 SUMO化 匿名 2013-05-23 12:23:18 Sumoylated 匿名 2013-05-23 12:24:58 Sumoylated 匿名 2013-05-23 12:26:38 Sumoylated 匿名 2013-05-23 12:28:18 Sumoylated热门同步练...
研究表明,TARBP2的类泛素化(SUMOylated)不会对成熟的的miRNA的产物有左右,但是会影响miRNA/siRNA的效用。其会引入Ago2来形成RNA沉默聚合体,并且会介导表达更多的miRNA前体结合到这一复合体上,从而进一步介导RNAi。 伤口愈合实验是体外研究细胞迁移的一个有用的实验。原理是人为的在铺板的单层细胞中制造一个空白的无...
Mechanistically, SUMOylated hnRNPM interacts with 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) to affect its localization and inhibit its phosphorylation, thus suppressing glycolysis. Accordingly, SUMO-deficient hnRNPM promotes colorectal cancer cell proliferation and tumorigenesis in mice...
localization21,38. We found that NKAP was also recruited by Bub3 to kinetochores. We further demonstrated that NKAP was SUMOylated in mitosis and the SUMOylated NKAP was required for the recruitment CENP-E to kinetochores. It has been reported that BubR1 interacts with CENP-E and contributes...
suppresses Smad4-mediated transcriptional activity by direct interaction with the sumoylated Smad4 and identify a novel role of Daxx in regulating TGF-尾 ... CC Chang,DY Lin,HI Fang,... 被引量: 205发表: 0年 Sumoylation activates the transcriptional activity of Pax-6, an important transcripti...
We began our studies with an alternative approach to screen systematically for sumoylated proteins. Utilizing a collection of yeast strains epitope-tagged with the tandem affinity purification (TAP) tag (22), we crossed traits useful for the detection of sumoylation into the TAP-tagged strains, im...
NKAP is SUMOylated predominantly in mitosis and the SUMOylation is needed for NKAP to bind CENP-E. A SUMOylation-deficient mutant of NKAP cannot support the localization of CENP-E on kinetochores or proper chromosome alignment. Moreover, Bub3 recruits NKAP to stabilize the binding of CENP-...
In the first strategy, SUMOylated MT3 was expressed and purified using Ulp1-mediated cleavage. In the second strategy, SUMOylated MT3 with a sortase recognition motif at the N-terminus of MT3 was expressed and purified using sortase-mediated cleavage. In the final strategy, the fusion protein ...
(2015) Sumoylated alpha-skeletal muscle actin in the skeletal muscle of adult rats. Mol. Cell. Biochem. 409, 59 - 66 Uda,Munehiro,Naito,... - 《Molecular & Cellular Biochemistry An International Journal for Chemical Biology》 被引量: 9发表: 2015年 Sumoylated alpha-skeletal muscle actin in ...
Ubiquitinated or sumoylated retinoic acid receptor alpha determines its characteristic and interacting model with retinoid X receptor alpha in gastric and ... (2004) Ubiquitinated or sumoylated retinoic acid receptor alpha deter- mines its characteristic and interacting model with retinoid X receptor alpha...