Background小分子泛素相关修饰物1、2和3(SUMO1、2和3)是泛素样蛋白家族的成员,其功能与泛素相似,也可以与靶蛋白共价结合。SUMO蛋白既可以单体与靶蛋白结合,也可以以赖氨酸连接成聚合物共价与靶蛋白结合。SUMO蛋白通过异肽键与其底物结合,首先需要通过E1复合物SAE1-SAE2激活,随后与E2酶UBE2I连接,最后通过E3连接酶...
在Western Blot(WB)分析中,若你的诱导表达的蛋白上有SUMO标签,选择哪个SUMO抗体取决于你使用的是SUMO1还是SUMO2/3标签。如果你的蛋白质是与SUMO1标签化的,应该使用针对SUMO1的抗体。相反,如果使用的是SUMO2/3标签,则应选择针对SUMO2/3的抗体。这是因为尽管SUMO1和SUMO2/3在结构上相似,它们在氨基酸序列上有差异...
SUMO-1 and SUMO-2,3 conjugation levels in brains of WT and Ubc9 transgenic mice with and without MCAO surgery.Yangja LeeYongshan MouDragan MaricDace KlimanisSungyoung AuhJohn M. Hallenbeck
SUMO-1, SUMO-2, and SUMO-3 来自 core.kmi.open.ac.uk 喜欢 0 阅读量: 63 作者: D Girdwood 摘要: I, David William Haxton Girdwood, hereby certify that this thesis, which is approximately 40,000 words in length, has been written by me, that it is a record of work carried out ...
We have found that during Ad5-infection, Mre11 is modified by SUMO-1 and SUMO-2/3 conjugation. Unexpectedly, SUMOylation of Mre11 is not exclusively dependent on E1B 55 kDa, E4 Orf6, or E4 Orf3, rather it seems to be influenced by a molecular interplay that involves each of ...
Epstein-Barr Virus latent membrane protein-1 (LMP1) interacts with the SUMO-conjugating enzyme Ubc9, which induces protein sumoylation and may contribute to LMP1-mediated oncogenesis. After analyzing human lymphoma tissues and EBV-positive cell lines, we
Cited in 20 publications. SUMO2/3 antibody for WB, IHC, IF/ICC, ELISA and reacts with human, mouse, rat.
SUMO2/3 Antibody Western Blot validation (1:1000 dilution) in Lymphoblastic cell line (Cat no:11251-1-AP) FH Shubham (Verified Customer) (03-13-2019) Good Applications:Western Blot, Cell Tissue Type:AC16 SUMO2/3 Antibody Western Blot, validation ( dilution) in AC16 (Cat no:11251-1-AP...
产品编号:4971S查看说明书 产品名称:SUMO-2/3 (18H8) Rabbit mAb .0订购此产品 供应商:CST 规格:100 ul 目录价:2972 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址:点击查看详细 打印此页关闭此页 上一个:β-Actin (13E5) Rabbit mAb[4970S/100 ul] ...
AMPKα-PINK1/parkin依赖线粒体自噬途径介导apelin-13促人主动脉血管平滑肌细胞增殖 目的:Apelin为G蛋白偶联受体APJ的内源性配体,本课题组前期报道ERK1/2及PI3K-Akt等信号通路介导apelin-13促血管平滑肌细胞增殖。单磷酸腺苷活化蛋白激酶AMPKα是能量代... 何璐 - 南华大学 被引量: 0发表: 0年来源...