Mechanism of Action of the Second-Generation Sulfonylurea Glipizide, The American Journal of Medicine, 75(5B): 46-54.Lebovitz HE, Feinglos MN. Mechanism of action of the second- generation sulfonylurea glipizide. Am J Med. 1983;75(5B):46-54....
Longitudinal evaluation of the effects of sulfonylurea therapy in subjects with type II diabetes mellitus Despite more than a quarter of a century of use in managing type II diabetes, the mechanism responsible for the hypoglycemic action of sulfonylurea agents ... Orville,G.,Kolterman - 《American...
In this paper, the sulfonylurea herbicides application profile, mechanism of action, Residues and de 翻译结果2复制译文编辑译文朗读译文返回顶部 正在翻译,请等待... 翻译结果3复制译文编辑译文朗读译文返回顶部 Sulfonylurea herbicides and acetanilide herbicides are currently two of the most widely used ...
Background:The presence of a complex phenotype of type 2 diabetes results from impaired insulin secretion and action, whereas the mechanism of action of sulfonylurea derivatives, most commonly used in the treatment of type 2 diabetes, is based on their a
Sulfonylurea receptors and mechanism of sulfonylurea action extrapancreatic actionsBinding of hypoglycemic sulfonylureas and their analogues to the sulfonylurea receptor in the 尾-cell plasma membrane mediates closure of ... M Koziarkiewicz,A Taczalska,A Piaseczna-Piotrowska - 《Exp Clin Endocrinol ...
Text Although earlier studies suggested various mechanisms of SU action, discovery of KATP channels by electrophysiology brought a break-through in understanding of the mechanism of action of SUs as well as the mechanism of glucose-stimulated insulin secretion. KATP channels were first reported in ...
It has been proposed that the combination of thiazolidinedione (TZD) therapy to metformin and sulfonylurea is beneficial due to each medication having a unique mechanism of action. Within the Veterans Affairs Hospital, specific criteria of use define when TZD therapy can be initiated. Most patients ...
Theoretical study on hydrolysis mechanism of three typical sulfonylurea herbicides; 三种磺酰脲类除草剂水解反应机理的理论研究 2. Effect of sulfonylurea herbicides on biological indicators characterizing the soil quality; 磺酰脲类除草剂对土壤质量生物学指标的影响 3. A low level multi sulfonylurea herbici...
Initially, discontinuation of insulin required high doses of glibenclamide (0.4 mg·kg−1·day−1) but with time doses have been able to be markedly reduced with the most recent dose being 0.11 mg·kg−1·day−1. The mechanism for this is unclear and contrasts with type 2 diabetes...
SUs exhibit effective glucose-lowering capability, albeit at the cost of an increased risk of hypoglycemia, caused by its glucose-inde- pendent mechanism of action, along with weight gain [1, 2]. DPP-4 inhibitors ameliorate glucose homeostasis by increasing both the a- and b-cell responsiveness...