Sugammadex: a novel ap- proach to reversal of neuromuscular blockade[J]. Expert Rev Neurother,2011,11( 2) : 185.Aniskevich S; Leone B J; Brull SJ.Sugammadex: a novel ap- proach to reversal of neuromuscular blockade.Expert Rev Neurother.2011.185-...
The US Food and Drug Administration (FDA) has approved sugammadex injection (Bridion, Merck) for the reversal of moderate or deep neuromuscular blockade induced by rocuronium or vecuronium during surgery, according to an agency news release. The FDA's Anesthetic and Analgesic Drug Products Advisory...
Conclusions:Our study showed that interventions, such as parallel processing during induction of anesthesia and room cleaning instead of linear processing and the use of the faster-acting sugammadex instead of the combination of...
Routine reversal (rocuronium or vecuronium):4 mg/kg IV once if recovery has reached at least 1 to 2 posttetanic counts (PTC) and no twitch responses to train-of-four (TOF) stimulation2 mg/kg IV once if recovery has reached reappearance of second twitch response to TOF stimulationImmediate...
Sugammadex (ORG-25969) is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults. AI解读 产品属性 名称和识别符 化学和物理性质 安全和危险性(GHS) 质检证书(CoA,COO,BSE/TSE 和分析图谱) 相关文档...
1.de Boer, H.D., van Egmond, J., van de Pol, F., et al.Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkeyBr. J. Anaesth.96(4)473-479(2006) 2.?ahin, H., Toman, H., Kiraz, H.A., et al.Effects of sugammadex on...
Sugammadex(Org 25969, tradenameBridion) is an agent for reversal ofneuromuscular blockadeby the agentrocuroniumingeneral anaesthesia. It is the firstselective relaxant binding agent(SRBA). Sugammadex Sodiumis thesodiumsalt form of the biologically inert, selective relaxant binding agent (SRBA) sugammadex...
Re-administration of Rocuronium or Vecuronium after Reversal (up to 4 mg/kg BRIDION) Minimum Waiting TimeNMBA and Dose to be Administered 5 minutes 1.2 mg/kg rocuronium 4 hours 0.6 mg/kg rocuronium or 0.1 mg/kg vecuronium If neuromuscular blockade is required before the recommended waiting ...
In infants, children, adolescents and adults receiving sugammadex 2 mg/kg following rocuronium 0.6 mg/kg, the mean time to neuromuscular blockade reversal was <1.9 minutes. The efficacy of sugammadex 2 mg/kg did not differ between patients with normal renal function and those with severe renal ...
A new reversal agent called sugammadex has been introduced. It specifically reverses rocuronium and, to a lesser extent, vecuronium, without any relevant effect on the duration of action of benzylisoquinolinium neuromuscular blockers. Its pharmacology has been summarized (19r). Among adverse effect...