In the investigation of sudden death in adults, channelopathies, such as long QT syndrome, have risen to the fore in the minds of forensic pathologists in
There is meager information in the literature regarding the characteristics and risk factors for injuries caused during epileptic seizures in adults. Previ... MY Neufeld,T Vishne,V Chistik,... - 《Epilepsy Research》 被引量: 223发表: 1999年 Medical causes of seizures. Presents an overview of...
12 Genetic causes of DCM include causative variants in genes encoding the sarcomere, desmosome, cytoskeleton, and mitochondria.13 Truncating variants in TTN account for up to 25% of idiopathic DCM, but onset typically occurs in the fifth and sixth decades of life. Arrhythmogenic cardiomyopathy ACM ...
can present as sudden, unexpected death. The associated mortality underscores the importance of early screening and identification of existing heart disease in athletes. Many athletes with preexisting heart disease are often asymptomatic, with a cardiac arrest being the initial manifestation of underlying ...
To identify P/LP in a broader set of genes without constraining to the Epilepsy and CMAR panels, we deployed GEM, an AI tool designed for whole genome-based diagnosis of Mendelian conditions [24], using HPO terms related to seizures and sudden cardiac death. Thirty-eight decedents (18%) ha...
Some characteristics are shared by patients at highest risk for SUDEP, such as refractoriness of the epileptic condition, occurrence of generalized tonic-clonic seizures, antiepi-leptic medication (polytherapy with antiepileptic drugs), young age, duration of the seizure disorder, early onset of ...
Athletes, particularly adolescents and young adults, are asked about use of illicit and performance-enhancing drugs. (See also the US Anti-Doping Agency) In girls and women, doctors look for delays in the onset of menstruation and presence of the female athlete triad (eating ...
Sudden cardiac death is defined as a natural death with sudden loss of consciousness within one hour of the onset of symptoms in a subject with or without known heart disease. The global incidence of sudden adult death is estimated at 20–100 cases per 100,000 person-years [1]. Sudden ...
Magnesium deficiency has been diag- nosed in infants and young children who had metabolic and nutritional disorders and presented with nonspecific findings including hyperirritability, failure to thrive, apathy, anorexia, sudden onset of apnea or respiratory distress, and tonic and clonic seizures ( 7...
It has been reported that the first infection is either asymptomatic or results in nonspecific symptoms, such as an eruptive disease, febrile seizures (FS), or febrile status epilepticus [1], [2], [3], [5], [11], [12]. Subsequent HHV-7 infection is mainly limited to lymphocytes, ...