Several risk factors can increase your likelihood of having acute arthritis. Some of these risk factors (like age) are out of your control. Others can be controlled with lifestyle modifications. In some cases, having one form of arthritis increases your likelihood of developing acute arthritis. A...
22 Nevertheless, genetic testing identifies such mutations in only about 20-25% of BrS patients.16 The increase in the transient outward potassium current (Ito) and the decrease in the L-type Ca2+ current (ICa,L) have also been postulated to contribute to the pathogenesis of BrS.15, 21 ...
2.3. The Role of Flow-Mediated Dilation and Rheopheresis in Endothelial Dysfunction Flow-mediated dilatation (FMD) refers to the increase in proximal (brachial) artery flow due to nitric oxide-mediated postischemic vasodilation; its disruption signals endothelial dysfunction. Rheopheresis is a therapeu...
. When participants were stratified by one unit of BMI, people with BMI ≥ 35 showed a clear increase in the risk of SCD which suggests that extreme obesity can increase the risk of SCD. People with BMI ≥ 35 only comprised 0.89% of the entire cohort which is much less than in western...
Mutations in KCNE5 cause modifications to potassium channels that lead to an increase in the Ito current and have been linked to BrS [43]. Functional KATP channels have an octameric subunit structure with four pore-forming subunits (Kir6.1) encoded by KCNJ8 and four sulfonylurea receptors (SUR...
(ILCOR), the European Parliament, and the World Health Organization (WHO) [11,12] recommend that CPR training should be included in secondary school curriculum in order to increase the number of people with Basic Life Support (BLS) skills, which in turn improves the rate of bystander-...
However, these same stringent procedures increase the confidence that the association signals detected represent true positive results. Furthermore, because only Caucasian cases and controls were examined, further studies are needed to determine whether these findings can be generalized to SCA in other ...