Background Immunotherapy has revolutionized patient treatment across cancer types; however, the majority of patients still do not respond, and the reasons for this are unclear. The gut microbiota has been linked to immunotherapy response in melanoma, but the contributing factors to a 'pro' or '...
Studies in both the U.S. and the U.K. have found that sweeteners like Splenda don’t cause cancer, which was once a concern. The FDA has done extensive testing on animals to make sure that Splenda does not have any neurological, carcinogenic, or reproductive effects. Even though sucr...
Studies in the 1970s and 1980s reported bladder cancer in rats given high doses of saccharin, which prompted the FDA in 1981 to pass a mandate that products containing saccharin carry a label warning about its potential as a human carcinogen [20]. However, it was later found that the ...
The relationship between artificial non-nutritive sweetener consumption and cancer risk goes back to the early 1970s when cyclamate was banned in the United Kingdom and the United States for being linked to bladder cancer in rats [29], although, to the best of our knowledge, carcinogenic ...
Cyclamates were banned by the FDA as a food ingredient in 1969 because the saccharin/cyclamate mixture was shown to cause cancer in experimental laboratory rats. The primary concern was that it could be toxic to some individuals who appear to metabolize cyclamate to cyclohexylamine. Neotame Neotame...