William A. BridgerBacterial expression of rat liversuccinly-Co A synthetaseα-subunit. Ryan D G,Bridger W A. Journal of Molecular Biology . 1991Ryan D G,Bridger W A.Bacterial expression of rat liversuccinly-Co A synthetaseα-subunit. Journal of Molecular Biology . 1991...
Western blot analysis was performed to validate the identity of translationally controlled tumor protein and ATP-specific succinyl-CoA synthetase beta subunit as differentially expressed hippocampal proteins and the identity of gamma-enolase isoform 1 as differentially expressed cortical protein. Caption: Figu...
Succinyl Coenzyme A synthetase (SCS) is a key mitochondrial enzyme. Defected SCS ADP-forming β subunit (SCS A-β) is linked to lethal infantile Leigh or leigh-like syndrome. However, the impacts of SCS A-β deficiency on mitochondria specifically in neurons have not yet been comprehensively ...
The 5 proteins with increased expression levels were identified as type II peroxiredoxin 1, ATP-specific succinyl-CoA synthetase beta subunit, rho GDP-dissociation inhibitor 1, heme-binding protein, and phosphatidylethanolamine-binding protein 1, and the 11 proteins with decreased expression levels were...
The former polypeptide's amino-terminal sequence closely matched a conserved portion of the -subunit of succinyl-CoA synthetase, which forms an acid-labile phosphohistidyl enzyme intermediate during its catalytic cycle. This identification was confirmed by the ability of succinate or ADP to specifically...
Succinyl-CoA synthetase (SCS) is the only mitochondrial enzyme capable of ATP production via substrate level phosphorylation in the absence of oxygen, but ... D Phillips,AM Aponte,SA French,... - 《Biochemistry》 被引量: 104发表: 2009年 Subunit interaction during catalysis. ATP modulation of ...
Localization and characterization of the mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic beta cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase. Arch. Biochem. Biophys. 398, 160–169 (2002). 18 Rustin, P., Bourgeron, T., Parfait, B., C...
Furthermore, using [gamma-32P]ATP as a phosphoryl donor, we observed that the alpha subunit of succinyl-CoA synthetase undergoes autophosphorylation at a histidine residue; co-provision of exogenous succinate and CoA resulted in pronounced dephosphorylation of the phosphorylated alpha...
Ramanath Majumdar and , William A. BridgerBiochemistry and Cell BiologyMAJUMDAR R. ET AL.: ' MITOCHONDRIAL TRANSLOCATION AND PROCESSING OF THE PRECURSOR TO THE ALPHA-SUBUNIT OF RAT LIVER SUCCINYL-COA SYNTHETASE ' BIOCHEM. CELL BIOL. vol. 68, no. 1, 1990, pages 292 - 299, XP003005845...
Recently, we described the properties of a mutant (H142N) of Escherichia coli succinyl coenzyme A (CoA) synthetase in which His-142 of the alpha-subunit was changed to Asn (Luo, G.-X., and Nishimura, J.S. (1991) J. Biol. Chem. 266, 20781-20785). The mutant enzyme was practically...