This multicopy gene has shown high diversity among different STs, making necessary to explore other genes to assess intraspecific diversity. This study evaluated the use of a novel genetic marker, succinate dehydrogenase (SDHA), for the typing and evaluation of the genetic diversity and genetic ...
DNA sequencing of the region directly downstream of the Anaplasma phagocytophilum (strain MRK) 16S rRNA gene identified homologues of sdhC and sdhD; however, further sequencing by gene walking failed to identify additional sdh gene homologues. The sequence downstream of sdhD identified a partial gene...
Succinate Dehydrogenase Gene Mutations Most cases of familialparagangliomaare caused by mutations in thesuccinate dehydrogenase(SDH; succinate : ubiquinone oxidoreductase) subunit genes (SDHB,SDHC,SDHD,SHDA, andSDHAF2), which make up portions of mitochondrial complex II.60,61The SDH genes are cons...
Germline mutations in the PTEN tumor-suppressor gene and germline variations in succinate dehydrogenase subunit D gene (SDHD-G12S, SDHD-H50R) are associated with a subset of Cowden syndrome and Cowden syndrome-like individuals (CS/CSL) a... W Yu,H Xin,Y Ni,... - 《Human Molecular Gene...
Genetic testing was done in 13 patients (86.7%); 10 (76.9%) were positive for mutations in succinate dehydrogenase (SDHx) subunits B, C, or D. Thirteen patients (86.7%) underwent surgery to remove the paraganglioma with no intraoperative morbidity or mortality; 1 additional patient underwent ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook succinate (redirected fromSuccinate dehydrogenase) Medical Acronyms Encyclopedia Wikipedia suc·ci·nate (sŭk′sə-nāt′) n. A salt or ester of succinic acid. ...
Succinate Dehydrogenase Assay Kit SDH Activity Assay Kit SDH活性检测试剂盒 基本信息 NACRES NA.84 General description【一般描述】 琥珀酸脱氢酶(SDH;酶代码 EC 1.3.5.1)是一种线粒体酶,在真核生物和细菌中催化琥珀酸氧化为延胡索酸,并携带电子从 FADH 到 CoQ。在通过三羧酸循环和电子传递链维持细胞能量代谢...
Succinate Dehydrogenase Assay Kit SDH Activity Assay Kit SDH活性检测试剂盒 基本信息 NACRES NA.84 General description【一般描述】 琥珀酸脱氢酶(SDH;酶代码 EC 1.3.5.1)是一种线粒体酶,在真核生物和细菌中催化琥珀酸氧化为延胡索酸,并携带电子从 FADH 到 CoQ。在通过三羧酸循环和电子传递链维持细胞能量代谢...
Succinate dehydrogenase (SDH)-deficient renal cell carcinoma is a recently recognized distinct subtype of renal cell carcinoma in the 2016 World Health Organization classification. It is associated with SDH gene germline mutations, which also cause paraganglioma/pheochromocytoma, gastrointestinal stromal tumor...
Succinate dehydrogenase(SDH) is part of respiratory complex II in the mitochondrion, and this enzyme complex is responsible for converting succinate to fumarate as part of the Krebs cycle. SDH is composed of four distinct proteins called SDHA, SDHB, SDHC, and SDHD.59A fifth gene calledSDHAF2,...