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Background: Prevalences of Alzheimer disease (AD) and vascular dementia (VaD) in China reportedly differ from those in Western countries. Objective: To estimate prevalence of AD and VaD in 4 regions of China. Design: Cross-sectional, population-based prevalence survey with a stratified, multistage...
This cohort consisted of 1347 patients, of whom 324 had VCI, and was followed for up to 30 months. Clinical and neuroimaging features defined three subtypes: vascular cognitive impairment, no dementia, ( n = 97), vascular dementia ( n = 101) and mixed neurodegenerative/vascular dementia ( n...
The ICD-10NA criteria for dementia, NINCDS-ADRDA guidelines for Alzheimer's disease (AD), and NINDS-AIREN criteria for vascular dementia (VaD) were employed. Three hundred and ninety-eight persons who had MMSE scores below the cutoff values were recruited into the phase II study, of whom ...
logistic regression./p pResults/p pThe reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimers disease, 238 of vascular dementia)....
adjustment and logistic regression.The reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimer's disease, 238 of vascular dementia). ...
dementia subtypes. In addition, the above-mentioned surveys focused on populations resident in the Northern half of the country, while Southern populations remain under-reported. The latter might be particularly important given the higher vascular mortality found in Southern Spain and the impact of ...
Moreover, previous studies have primarily focused on all-cause dementia (ACD) and Alzheimer’s disease (AD), but the potential of metabolites to predict vascular dementia (VaD) has not yet been investigated. Therefore, there is a clear need to conduct comprehensive, large-scale metabolomic ...
vascular dementia (VD)In the past years, the possible involvement of inflammation in the pathogenesis of dementia has been the subject of several investigations. However there are restricted data about the profile of the inflammatory and soluble proteins in well evaluated Alzheimer's disease (AD), ...
of cortical atrophy, cell type-specific expression of proteins, vascular damage and clinical outcomes. These results highlight the importance of neuronal plasticity, microglial impairment, innate immune activation, RNA processing, choroid plexus and blood–brain barrier dysfunction in AD pathogenesis, and...