Xenopus neurulaLateral plate mesodermSignaling by members of TGF-β superfamily requires the activity of a family of site-specific endopeptidases, known as Subtilisin-like proprotein convertases (SPCs), which cleave these ligands into mature, active forms. To explore the role of SPCs in lateral ...
Serum albumin is synthesized as a larger precursor form, proalbumin, which undergoes proteolytic processing at a dibasic site by a hepatic proprotein convertase within the secretory pathway to generate the mature form. Although furin, a member of the subtilisin-like proprotein convertase (SPC) family...
Human Subtilisin-Like Proprotein Convertase, PACE4 (SPC4) Gene Expression Is Highly Regulated through E-Box Elements in HepG2 and GH4C1 Cells 1 PACE4 (SPC4) is a member of the mammalian subtilisin-like proprotein convertase (SPC) family, which participates in maturation of precursor proteins....
Subtilisin/kexin-like protease PC9 Basic informationMore.. Product Name:Subtilisin/kexin-like protease PC9 Synonyms:ANTI-PCSK9 (C-TERM) antibody produced in rabbit;NARC1;NARC-1;Neural apoptosis-regulated convertase 1;PCSK9;Proprotein convertase PC9;Proprotein convertase subtilisin/kexin type 9;PSEC0052...
Kexins have two major domains: a peptidase S8 catalytic domain, and a proprotein convertase domain. Kexin-type enzymes, first identified in the yeast Saccharomyces cerevisiae [11], play an important role in post-translational modification in eukaryotes. Secreted proteins in eukaryotes are often ...
Subtilisin-like proprotein convertase 4 subtilisin/kexin isozyme-1 Subtilisin/kexin-isozyme 1 Subtilisin/kexin-like protease PACE4 Subtilisin/kexin-like protease PC5 Subtilisin/kexin-like protease PC7 subtilising Subtilisins Subtilisins Subtilism subtility subtilization subtilize subtilized Subtilizer ...
1993 . cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells . ... Lusson,Vieau,Hamelin,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 465发表: 1993...
Subtilisin-like proprotein convertase PACE4 (SPC4) is a candidate processing enzyme of bone morphogenetic proteins during tooth formation The temporospatial expression of PACE4, a member of the mammalian subtilisin-like proprotein convertase family, in the developing rat molar tooth was deter... T ...
Proprotein convertase subtilisin/kexin type 9 (PCSK9),is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a
47Altmetric Metrics Abstract Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins that encompass a wide range of enzymatic activities frequently associated with pathogenic phenotypes. We present the structural and functional characterisation of a subtilase autotransporter...