chymotrypsininhibitor-2肽类An off-lattice dynamic Monte Carlo (MC) method is used to investigate the conformational dynamics of chymotrypsin inhibitor 2 (CI2) and subtilisin in both free and complex forms over two time windows, referring to short and long time scales. The conformational dynamics ...
英文名:Chymotrypsin 别名:糜蛋白酶;胰凝乳蛋白酶 ,α-糜蛋白酶 外文名:Chymotrypsin 适应症: 1.用于创伤或手术后伤口愈合、抗炎及防止局部水肿、积血、扭伤血肿、乳房手术后浮肿、中耳炎、鼻炎等。 2.本品对眼球睫状韧带有选择性松解作用,故可用于白内障摘除,使晶状体比较容易地移去。
(1993) Biosci. Biotech. Biochem. 57, 522-524], is the first SIL inhibitor demonstrated to show marked inhibitory activity toward alpha-chymotrypsin, in addition to strong inhibitory activity toward subtilisin BPN', a common property of inhibitors of the Streptomyces subtilisin inhibitor (SSI) ...
The inhibitory activity of Tk-serpin increases as the temperature increases up 100 °C. 关键词: Serpin Proteinase inhibitor Thermococcus kodakaraensis Hyperthermophilic archaeon Subtilisin Association rate constant DOI: 10.1016/j.bbapap.2010.11.003 被引量: 11 年份: 2011 ...
1994: Primary structure and inhibitory properties of a subtilisin-chymotrypsin inhibitor from Streptomyces virginiae European Journal of Biochemistry 226(2): 627-632 Kassell, B. 1970: [66b] Bovine trypsin-kallikrein inhibitor (kunits inhibitor, basic pancreatic trypsin inhibitor, polyvalent inhibitor ...
Two subtilisin inhibitors and two trypsin-chymotrypsin inhibitors were purified from seeds of Vigna unguiculata subsp. cylindrica. A third subtilisin inhib... G H.,Vartak,and,... - 《Archives of Biochemistry & Biophysics》 被引量: 75发表: 1980年 SUBTILISIN INHIBITOR FROM SEEDS OF BROAD BEAN (...
Eder et al., "Hydrolysis of Small Peptide Substrates Parallels Binding of Chymotrypsin Inhibitor 2 for Mutants of Subtilisn BPN'" Federation of European Biochemical Societies 335(3):349-352 (1993). Forsberg et al., "An Evaluation of Different Enzymatic Cleavage Methods for Recombination Fusion Pro...
The potential individual substrate-binding pockets of Ssp, were identified by overlaying the structure of subtilisin BPN’ in complex with the inhibitor CI2 (PDB: 1LW6)44with the subtilase domain of Ssp. The bound reactive site loop of CI2 provided a guide to the subsite positions in Ssp (Fig...
A site-directed mutagenesis strategy was employed to obtain four mutants of wheat subtilisin/chymotrypsin inhibitor (WSCI), with the aim to produce inactiv... N Bruni,AD Maro,S Costantini,... - 《Biochimie》 被引量: 8发表: 2009年 Construction and screening of a multi-point site- specific ...
A kinetic study was conducted to investigate the properties of subsites S1′ and S2′ of α-chymotrypsin and subtilisin BPN′, which were deduced from model complexes with a pancreatic trypsin inhibitor and a hexapeptide substrate, respectively. For this purpose, and (AA, various amino acid res...