Wu, YuanhengChem Engn Zhongshan 528458 Peoples R ChinaCao, HuaGuangdong Pharmaceut Univ Sch Chem &The Journal of Organic ChemistrySubstrate-controlled selectivity switch in a three-component reaction:a Ag-catalyzed strategy for the synthesis of functionalized imidazoles. WANG C,WANG E,CHEN W,et al...
Christian Ltiken, Christina Moberg. Silaborations of 1,3- enynes-substrate controlled allene/1,3-diene selectivity[J]. Org Lett, 2008,10(12) : 2505.Luken, C.; Moberg, C. Silaborations of 1,3-enynes - Substrate controlled allene/1,3-diene selectively. Org. Lett.s, 2008, 10, 2505-...
Antigen presentation in Syrian hamster cells: substrate selectivity of TAP controlled by polymorphic residues in TAP1 and differential requirements for loa... (1999) Antigen presentation in Syrian hamster cells: substrate selectivity of TAP controlled by polymorphic residues in TAP1 and differential ...
In nature,enzymes often use substrate selectivity to transform specific metabolites in complex mixtures.However,laboratory-based approaches implementing substrate selectivity using small molecule reagents and catalysts to discriminate between compounds in equilibrium can be challenging if the reactivity of the ...
With this assay, we show that PATs localizing to different membrane compartments display remarkable substrate selectivity, which is the basis for PMP compartmentalization. Our findings uncover a mechanism governing protein localization and establish the basis for innovative drug discovery....
High Selectivity Patterned Substrate Epitaxy of In x Ga1 − x As / GaAs ( 0 ≤ x ≤ 1 ) by Conventional LPOMVPE M.F. Zybura et al., High Selectivity Patterned Substrate Epitaxy of In X Ga 1 x As/GaAs(O X 1) by Conventional LPOMVPE , J. Electroc...
The molecular mechanism of substrate selectivity of PLR/PrR has attracted particular interest owing to the key role of these enzymes in lignan biosynthesis. However, the lack of structural results—especially for PLRs/PrRs in complex with different substrates—has limited our understanding of the mecha...
We have created phoslactomycin polyketide synthaseヾerived in vitro systems and studied their substrate selectivity. We were able to produce various phoslactomycin derivatives with altered sideヽhain lengths and characterized the transacylation and hydrolysis activity of the involved acyltransferases for ...
inside the cell, where structurally analogous metabolites are present. Also, the fact that all four phenylpropanoids can still access the central cavity of MtABCG46 WT and F562L clearly reveals the presence of additional molecular mechanisms behind the observed selectivity in subsequent stages of the...
Substrate selectivity can be explained by the relative rate constants. • Electrostatics accounts for a small part of the substrate selectivity. • Both NODD and CODD induce the same conformational change in PHD2. Abstract HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate...