摘要: 2' and 4'-Substituted arylfurans react with DMAD in the presence of Lewis acid to afford Diels-Alder adducts with good yields; a subsequent spontaneous or an acid-induced β-elimination leads to polysubstituted phenylphenols.关键词: DIELS-ALDER REACTION FURAN DOI: 10.1055/s-1997-1403 ...
Het represents a heterocyclic radical being defined in the Claims and the aryl group is represented by phenyl being optionally substituted with alkyl containing 1 to 6 carbon atoms or with a halogen, further their N-oxides, stereochemically isomeric forms and pharmaceutically acceptable acid addition ...
For wound healing assay, 1 × 104 HUVECs were seeded with gelatin on a six-well plate. Upon reaching about 90% confluence, the cell monolayer was scraped by a sterile 0.1 mL pipette tip to create wounds, and HUVECs were seeded with or without different concentrations of ...
In this paper, we describe both new as well as described in our previous works 1,8-naphthalimide derivatives substituted at the 3-C position with imine or β-ketoenamine unit in order to demonstrate a broader scope of research enabling of analysis between the structure-properties relationship rele...
Compounds of formula I, wherein R 1 , R 2 , R 3 , R 4 , R 5 , X, Y, and Ar are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/...
-NRQN2RQN3 is independently piperidino, piperazino or morpholino, and is optionally substituted with one or more -RQNR substituents, where each -RQNR is... I Collins,J Reader,T Matthews,... 被引量: 0发表: 2017年 加载更多来源期刊 Acta Crystallographica 研究点推荐 flexible ethylene spacers...
The introduction of an O-aryl group or an S-aryl was then carried out by nucleophilic substitution with (thio)phenolic compounds, in the presence of potassium carbonate as a base. Whereas substitution with phenol derivatives required high temperature to proceed, substitution with thiophenol ...
Fluorescent live-cell microscopy studies showed that cationic porphyrins with 1–3 positive charges bind to the cell membrane of E. coli, but are not internalized. On the contrary, the tetra-cationic porphyrin (4) permeates through the membrane of the cells. The contrast in the interaction of...
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Reactions of [Ru(C5Me5)Cl]4 with siloxy-substituted 1,3- or 1,4-dienes were found to lead to incorporation of the organic fragment as either a diene or dienyl ligand. From the reaction involving 3-(R2R'SiO)-1,4-C5H7 (R = R' = CH3; R' = t-C4H9), a simple diene complex ...