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In this study, we assessed the efficacy and safety of ASP0028 co-administered with suboptimal-dose of tacrolimus in the Cynomolgus monkey renal transplantation model. Seven animals in group-1 or group-2 received mono-tacrolimus 1.0 mg/kg once a day (QD), or ASP0028 0.6 mg/kg plus ...
cent of recipients of prevention services in antenatal settings receivedasuboptimalsingle-dose antiretroviral regimen, highlighting the importance of improving[...] daccess-ods.un.org daccess-ods.un.org 2009 年,30%的接受产前预防服务的人接受了欠佳的单剂抗反转录病毒药 物治疗,凸显了获得更有效组合方案...
Influence of Timing and Dose of Thyroid Hormone Replacement on Mental, Psychomotor, and Behavioral Development in Children with Congenital Hypothyroidism To evaluate the influence of initial and postinitial treatment factors on cognitive, psychomotor, and psychological outcome in schoolchildren with congenit...
dose for an adequate period of time. There is compelling evidence that this is less likely to be achieved with a TCA than with an SSRI. Given the morbidity and burden caused by depression, centrally coordinated naturalistic studies to investigate the outcomes of suboptimal antidepressant use should...
On the basis of the total rhFSH consumption, patients were divided into three groups: Group A: 22 women requiring a cumulative dose of rhFSH >3500 IU; Group B: 15 patients requiring 2000–3500 IU; Group C (control): 23 women requiring <2000 IU. The presence of v-βLH was evaluated ...
Effects of EGCG alone and in combination with a suboptimal dose of GA in established EAE.Antonia JanssenSebastian FiebigerHelena BrosLaura HertwigSilvina RomeroSuarezIsabell HamannCoralie ChanvillardJudith BellmannStroblFriedemann PaulJason M. Millward...
". Caregiver: "[My child] has to be able to be able to push it down to get the full dose". Adult with asthma: "I wish they would just combine the long lasting with the rescue inhaler all in one instead of having to carry on with so many pumps". Adult with asthma: "[My ideal...
Among rampril users, only 36.8% of patients (53/144) were on an optimal dose. Although atherosclerotic risk factors were prevalent in patients with PAD, we found that patients received sub-optimal use of risk reduction treatments. Effective strategies to encourage health professionals to use these...
Moreover, a recent study has demonstrated a dose–response relationship between lower adherence and higher cardiovascular disease risk; the non-adherent group had a 1.57 times higher cardiovascular disease risk than the adherent group [50]. To improve adherence, individual appointments for outpatient ...