aFurthermore, in the absence of WRN, leading- and lagging-strand DNA synthesis are uncoupled at replication forks, and POT1 is required for efficient replication of C-rich telomere strands 此外,在没有WRN时,铅和绝热材料子线脱氧核糖核酸综合被拆在复制叉子,并且POT1为富有C的telomere子线的高效率的复...
Aberg MAI, Pedersen NL, Torén K, Svartengren M, Bäckstrand B, Johnsson T et al (2009). Cardiovascular fitness is associated with cognition in young adulthood. Proc Natl Acad Sci USA 106: 20906–20911. Arida RM, Gomes da Silva S, de Almeida AA, Cavalheiro EA, Zavala-Tecuapetla C...
For qPCR, first-strand complementary DNA was synthesised from 2 μg RNA using 100 units M-MLV-RT (Applied Biosystems, Scoresby, VIC, Australia)30 and used as a template for qPCR. Potential primer sequences were elucidated using Beacon Designer software (PREMIER Biosoft, Palo Alto, CA, USA)...
He also explained how each strand of spaghetti always grows to the same length thanks to years of hard work by generations of growers. This is believed to be one of the first times the medium of television has been used to stage an April Fools Day hoax. In Context The origins of April...
(R2> 0.99). This method had acceptable precision and accuracy, good recovery from the plasma matrix, and stability during the analytical procedures. When the validated method was applied to the bioequivalence study of two felodipine tablet formulations in 30 healthy male Korean subjects, the results...
This study evaluated acute cardiac stress after a high-intensity interval training session in patients with type 2 diabetes (T2D) versus healthy controls. High intensity aerobic exercise was performed by 4 × 4-min intervals (90–95% of maximal hea
42. Blomstrand, E. A role for branched-chain amino acids in reducing central fatigue. J Nutr 136, 544S–547S (2006). 43. Javitt, D. C. Glutamate as a therapeutic target in psychiatric disorders. Mol Psychiatr 9, 984–997, 979 (2004). 44. Schousboe, A. Role of astrocytes in ...
2.9. DNA Strand Breaks (Comet Assay) The modulation of background and total DNA strand breaks was assessed in whole blood. Additionally, to monitor alterations in cell sensitivity to reactive oxygen species-induced DNA damage, the total DNA strand breaks in PBLs were analyzed after H2O2 challenge...
Serum apoB-100 was measured by a human apoB ELISA pro kit (cat. 3715-1HP-2, Mabtech AB, Nacka Strand, Sweden) with an intra-/inter-assay precision of 2.0% and 10.0%. Plasma alkylresorcinol homologues C17:0, C19:0, C21:0, C23:0, C25:0 and their sum (total alkylresorcinols) were...