STXBP5-AS1 geneWe aimed to detect Attention-deficit/hyperactivity (ADHD) risk-conferring genes in adults. In children, ADHD is characterized by age-inappropriate levels of inattention and/or hyperactivity-impulsivity and may persists into adulthood. Childhood and adulthood ADHD are heritable, and are...
STXBP5-AS1乳腺癌竞争性内源RNA信号通路乳腺癌是一种多发于女性的恶性肿瘤,是女性中最常见的恶性肿瘤之一,目前由于乳腺癌的病因还未完全清楚,对于乳腺癌的治疗还存在着不尽人意的副作用,因此找到新的治疗乳腺癌策略已迫在眉睫.越来越多的研究表明Lnc RNA在肿瘤的发生与发展中发挥着重要的作用,其有望成为治疗肿瘤...
STXBP5-AS1Previous studies suggest the tumor suppressor role of long non-coding RNA (lncRNA) STXBP5-AS1 in cervical and gastric cancer, but its expression pattern and functional mechanism are still elusive in pancreatic cancer (PC). Relative expression of STXBP5-AS1 in PC both in vivo and...
Screening the target genes of miR-4425 and Rh2 revealed that Rh2, STXBP5-AS1, and miR-4425 consistently regulated tumor suppressor RNF217 at both the RNA and protein level. Conclusion LncRNA STXBP5-AS1 is upregulated by Rh2 via promoter hypomethylation and acts as a ceRNA, sponging the ...