implant) The data set forth in Tables 1 through 4 demonstrate that the osteogenic device can be sterilized by gamma irradiation as evidenced by the retention of biological activity of the OP-1 containing devices. A decrease in osteogenic potential was seen in some groups. In general, the highes...
an implant or the like. The gear wheel portions200engage into recesses202of a rod204which may be moved in the longitudinal direction, and which may be directly connected to the third shaft for modifying the geometry (diameter) of the ablation device. It should be noted that the gear wheel ...
, intraperitoneal, or intramuscular implants; it may be shaped to span a non-union fracture or to fill a bone defect. In bone formation or conduction procedures, the material is slowly absorbed by the body and is replaced by bone in the shape of or very nearly the shape of the implant....
WO/1998/051237 November, 1998 CATHETER-FILTER SET HAVING A COMPLIANT SEAL WO/1998/055175 December, 1998 TEMPORARY INFLATABLE FILTER DEVICE AND METHOD OF USE WO/1999/009895 March, 1999 FAST-DETACHING ELECTRICALLY INSULATED IMPLANT WO/1999/022673 May, 1999 TEMPORARY VASCULAR FILTER GUIDE WIRE WO/1999...
of screws is rather decreased, especially in osteoportic bones. The adhesive force of screws may be supported by adhering the outer surface of bones on a great area with the implant (e.g. a plate) by means of the inventive kits and/or adhesives, or screws may even totally be dispensed...
addition, administration may be by periodic injections of a bolus of the renal therapeutic agent, or may be made more continuous by intravenous or intraperitoneal administration from a reservoir which is external (e.g., an i.v. bag) or internal (e.g., a bioerodable implant or implanted ...
The implant model in rats exhibits a controlled progression through the stages of matrix induced endochondral bone development including: (1) transient infiltration by polymorphonuclear leukocytes on day one; (2) mesenchymal cell migration and proliferation on days two and three; (3) chondrocyte appeara...
The implant model in rats exhibits a controlled progression through the stages of matrix induced endochondral bone development including: (1) transient infiltration by polymorphonuclear leukocytes on day one; (2) mesenchymal cell migration and proliferation on days two and three; (3) chondrocyte appeara...
The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing...
This invention involves osteogenic devices which, when implanted in a mammalian body, can induce at the locus of the implant the full developmental cascade of endochondral bone formation and bone marrow differentiation. Suitably modified as disclosed herein, the devices also may be used to induce car...