Structure-function analysis of HscC, the Escherichia coli member of a novel subfamily of specialized Hsp70 chaperones. J Biol Chem. 2002; 277 :41060–41069.Kluck,CJ,Patzelt,H,Genevaux,P,Brehmer,D,Rist,W,Schneider-Mergener,J,Bukau,B,Mayer,MP.Structure-function analysis of HscC, the ...
针对不同的项目,博朗可能从下列 方法中挑选两个进行估计:工作分解 结构法 (W ork Breakdown Structure, WBS),功能点(Function Point)分析法,基于组件的规模估计(Component Sizing),历史数据分析法(Historical Analysis)或宽带德尔菲法(Wide Band Delphi)。 bleum.com [...] establishment of a robust monitoring...
Full size image SEC-MALS analysis showed that PorXFjincubation with Zn2+induced dimerization, similarly to PorXPg33(Fig.2). Interestingly, dimers induced by phosphorylation (AcP + Mg2+) and Zn2+eluted at different volumes, suggesting that they adopt different conformations, which confirms SA...
2 MD simulation (200 ns) of the SHOC2 complex, cryo-EM electron density maps of SHOC2-PP1C contacting surfaces of T411 and N-terminal region RVXF motif, and AUC analysis of PP1C pairwise interactions with complex members. a, An overview of the MD simulation system for the SHOC2 ...
Our analysis compares the results for the various samples. We split each sample in two based on the median of the physical property of interest, and analyzed the differences in the SF shape and slope, and their possible causes. Results. While the SF shape does not change with depth, it ...
Structure-Function Analysis of the THAP Zinc Finger of THAP1 by Site-directed Mutagenesis–We have previously shown that the eight invariant residues that define the THAP domain are absolutely required for DNA binding activity (7). To get further insights into the role of other residues in DNA ...
Products for RNA Structure/Function Analysis RNA Structure Has a Biological Role RNA structure is thought to play a central role in many cellular processes, including transcription initiation, elongation and termination, mRNA splicing, and retroviral infection of euka...
The utilization of computer modeling, site-directed mutagenesis, inhibition kinetic analysis and reaction metabolite analysis allows us to better understand the structure–function relationship between aromatase and its inhibitors. Our results have helped in determining how steroidal and nonsteriodal aromatase...
The mutational analysis of key residues in the CadC-DNA complex supports the protein-DNA interactions suggested by the superimposition of CadC withpho-box DNA shown in Fig.5b. To obtain more detailed insight into specific interactions between the CadC DBD and the Cad1 DNA site we generated a ...
GCAT genesT A C G GCAT Article Structure-Function Mutational Analysis and Prediction of the Potential Impact of High Risk Non-Synonymous Single-Nucleotide Polymorphism on Poliovirus 2A Protease Stability Using Comprehensive Informatics Approaches Amna Younus 1, Saba Munawar 2, Muhammad Faraz Bhatti 1,*...