N. (1957). Structure of vitamin B 12 . Proc. R. Soc , 242 , 228–63.Hodgkin DC , Kamper J ,MacKay M. Pickworth J . 1956. Structure of vitamin B12. . Nature 17∶64 - 66.Hodgkin, D. C., Pickworth, J. & Robertson, J. (1955). Structure of vitamin B 12 . Nature, Lond...
The ATP-binding cassette (ABC) transporter BtuCD mediates the uptake of vitamin B12across the inner membrane ofEscherichia coli. Previous structures have shown the conformations of apo states, but the transport mechanism has remained unclear. Here we report the 3.5 Å crystal structure of the ...
The structure of the monomeric oxygen adduct of vitamin B12r: A single crystal ESR studyFrom ESR single crystal spectra of B 12rO 2 substituted in B 12b the structure of the Co O O fragment was determined at 190°C. The g and A Co tensors were found to be non-coaxial with the ...
Electronic structure of the coenzyme vitamin B~1~2 and related systems Part II: A corrin model system Hansen,L.,M.,... - 《Journal of Molecular Structure》 被引量: 1发表: 1998年 Electronic Structure of the Coenzyme Vitamin B12 and Related Systems. 1. Co(DH)2(L)(R) Compounds (DH =...
In Bacillus megaterium, the synthesis of vitamin B(12) (cobalamin) and sirohaem diverges at sirohydrochlorin along the branched modified tetrapyrrole biosynthetic pathway. This key intermediate is made by the action of SirC, a precorrin-2 dehydrogenase that requires NAD(+) as a cofactor. The s...
The crystal structure of Escherichia coli BtuF, the protein that binds vitamin B_(12) and delivers it to the periplasmic surface of the ABC transporter BtuCD, reveals a bi-lobed fold resembling that of the ferrichrome binding protein FhuD. B_(12) is bound in the "base-on" conformation ...
The number of known three-dimensional structures of vitamin B6-dependent enzymes has doubled in the past two years. A fourth type of fold for B6-dependent enzymes, involving a TIM-barrel domain, has been discovered. Alanine racemase is the first known representative of this new fold. Significan...
In the second part, the structure-function relationship of vitamin D was analyzed based on the ligand struc-ture, in particular by using systematic conformational analysis as a tool. On the basis of the conformational analysis of the vitamin D side chain and studies using conformationally ...
(1994). How a protein binds B12 -- a 3.0 Angstrom X-ray structure of B12- binding domains of methionine synthase. Science 266, 1669-1674.How a protein binds b-12-a 3.0-angstrom x-ray structure of b-12-binding domains of methionine synthase. Drennan CL,Huang S,Drummond JT,Matthews RG...
It should also be noted that HpaC of S. tokodaii, which prefers FMN to FAD, contains a 310 helix in the same position as α4 in TftC. Show abstract Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B<inf>12</inf> 2018, Nature Communications Microbial production...