Role of a low-molecular-weight stimulator of phosphofructokinase. 1. Recycling of metabolites between fructose 6-phosphate and triose phosphates has been investigated in isolated hepatocytes by the randomization of carbon between C((1)) and C((6)) of glucose formed from [1-(14)C]galactose. 2...
The glucose transporter GLUT1 catalyses facilitative diffusion of glucose into erythrocytes and is responsible for glucose supply to the brain and other organs. Dysfunctional mutations may lead to GLUT1 deficiency syndrome, whereas overexpression of GLUT1 is a prognostic indicator for cancer. Despite de...
Glucagon-like peptide 1 (GLP-1) regulates glucose homeostasis through the control of insulin release from the pancreas. GLP-1 peptide agonists are efficacious drugs for the treatment of diabetes. To gain insight into the molecular mechanism of action of GLP-1 peptides, here we report the crysta...
The configurations of two anomeric positions are set simultaneously, resulting in the formation of a double glycoside. The three-dimensional structure of the Escherichia coli OtsA, in complex with both UDP and glucose-6-phosphate, reveals the active site at the interface of two β/α/β domains...
The sugar transporters of the PTS (enzymes II) have been classified into five phylogenetically different superfamilies [21,120,121]: (1) Glucose/Fructose/Lactose (GFL); (2) Glucitol, (3) Ascorbate/Galactitol (AG); (4) Mannose/Sorbose/Fructose (MSF, Man-PTS); (5) Dihydroxyacetone. Represen...
dTDP- d-glucose 4,6-dehydratase (RmlB; EC 4.2.1.46) is the second enzyme in the dTDP- l-rhamnose biosynthetic pathway. The structure of Salmonella enterica serovar Typhimurium RmlB had been determined to 2.47 resolution with its cofactor NAD + bound. The structure has been refined to a ...
Aconitan A did not affect plasma insulin levels in normal, glucose-loaded and alloxan-induced hyperglycemic mice and gave no influence on insulin binding t... H Hiroshi,K Masako,S Yutaka,... - 《Journal of Ethnopharmacology》 被引量: 118发表: 1989年 The effects of Rhizoma Zingiberis on pha...
Effect of ultimate pH on the physicochemical and biochemical characteristics of turkey breast muscle showing normal rate of postmortem pH fall. TurkeysPostmortem ChangesGlycogenGlucose-6-PhosphateHydrogen-Ion ConcentrationColorMeatThis experiment aimed to study the effect of ultimate pH (pH(u)) on the....
The crystal structure of C-C-A-T-T-A-A-T-G-G. Implications for bending of B-DNA at T-A steps. The single-crystal X-ray analysis of trigonal C-C-A-T-T-A-A-T-G-G, and its comparison with orthorhombic C-G-A-T-T-A-A-T-C-G, have shown that the A-T-T-A-A-... DS...
use of glucose for the improvement of the structure and the nakmmbarkeit of hairCORTEKAR, HANS-WOLFGANG, LANGENFELD, DE