Trounson, The fine structure of human embryonic stem cells. Reprod Biomed Online, 2002. 4(1): p. 56-61.H. Sathananthan, M. Pera, A. Trounson, The fine structure of human embryonic stem cells, Reprod. Biomed. Online 4 (2002) 56-61....
The discovery that stem cells from dental pulp are capable of differentiating into endothelial cells raised the exciting possibility that these cells can be a single source of odontoblasts and vascular networks in dental tissue engineering. These so-called mesenchymal stem cell populations have been id...
Although the existence of the limbal stem cell (LSC) niche is accepted, precise knowledge of its three-dimensional (3D) architecture remains incomplete. The LSC niche was explored on freshly excised and organ-cultured corneoscleral rims from human donors (n = 47), pigs (n = 15) and mice ...
RNA structure is intimately connected to each step of gene expression. Recent advances have enabled transcriptome-wide maps of RNA secondary structure, called ‘RNA structuromes’. However, previous whole-cell analyses lacked the resolution to unravel th
However, the signals mediating the initial minus end-directed, dynein-dependent transport of the mRNA from nurse cells into the oocyte have remained unknown. Here, we show that a 67-nt stem-loop in the oskar 3' UTR promotes oskar mRNA delivery to the developing oocyte and that it shares ...
Additionally, CAP shows prom- ising anticancer activities through apoptosis and cell cycle arrest, which have been shown to lead to the destruc- tion of tumor cells in both in vitro and in vivo experiments9–13. Both anticancer activity and the inactivation of microbes by CAP are due to the...
Hoxa9 Transduction Induces Hematopoietic Stem and Progenitor Cell Activity through Direct Down-Regulation of Geminin Protein Hoxb4, a 3'-located Hox gene, enhances hematopoietic stem cell (HSC) activity, while a subset of 5'-located Hox genes is involved in hematopoiesis and leuk... Y Ohno,S ...
Human telomerase is a RNA–protein complex that extends the 3′ end of linear chromosomes by synthesizing multiple copies of the telomeric repeat TTAGGG1. Its activity is a determinant of cancer progression, stem cell renewal and cellular aging2,3,4,5. Telomerase is recruited to telomeres and ...
Moreover, their coexpression increased γ-secretase activity in both Drosophila and mammalian cells [61], [62] and reconstituted activity in yeast [64]. Because yeast have no such protease activity and contain no apparent orthologs of these metazoan proteins, these findings strongly suggested that ...
Comparison of root- and stem-wood rays of Larix decidua showed root-wood had fewer ray tracheids, taller, wider but shorter ray parenchyma cells, and larger cross-field pits than stem-wood. The implications of these differences are considered in relation to the identification and function of ...