Use of a reducing sugar to improve the structure and the wet combability of hairCORTEKAR HANS-WOLFGANG
The crystal structure of an N-terminal truncated derivative of TrmB (amino acids 2-109 deleted; TrmB(delta2-109)) was solved at 1.5 A resolution. This protein has lost its DNA binding domain but has retained its sugar recognition site. The structure represents a novel sugar-binding fold. ...
S3a,b). The entire structure of AglΔDCD-UCD was β-sheet rich and consistent with the observed CD spectra (Fig. 2a). The right-handed β-helix fold is a common structural class for carbohydrate-binding proteins called “CASH (carbohydrate-binding proteins and sugar hydrolase)”17, and ...
Glu540 to be close to the binding site and thus predict them to play a key role in chitobiose hydrolysis with Glu540 acting as a proton donor to the substrate, while Asp539 restrains its acetamido group in a specific orientation by hydrogen bonding with N2 of the nonreducing sugar [11]...
The structures differ in the position of a structurally conserved substrate-binding domain that is suggested to play a central role in sugar transport. In addition, molecular dynamics simulations suggest a potential pathway for substrate entry from the periplasm into the bcMalT substrate-binding site...
Gangliosides in the outer leaflet of the plasma membrane of eukaryotic cells are essential for many cellular functions and pathogenic interactions. How gangliosides are dynamically organized and how they respond to ligand binding is poorly understood. Us
This paper reviews the structure and biological activities of natural plant polysaccharides.The biological activities,such as anti-tumor,immunological regulation,anti-fatigue,reducing blood sugar,anti-virus and anti- oxidation,etc,are mainly introduced.关键词: plant polysaccharide structure biological activity...
Electronic Structure of H_2S, SF_2, and HSF and Implications for Hydrogen-Substituted Hypervalent Sulfur FluoridesIt is well known that hypervalent molecules are moBethDepartmentA.DepartmentLindquist... Beth,A.,Lindquist,... - 《Journal of Physical Chemistry A》 被引量: 0发表: 2014年 Multi-OMI...
Acetylation contributes to the bioactivity of numerous medicinally important natural products. However, little is known about the acetylation on sugar moieties. Here we report a saponin acetyltransferase from Astragalus membranaceus. AmAT7-3 is discovere
As seen on the right, when superimposed onto chain B of 6V8Q, the proximal 1-phospho-GlcNAc group of lipid A in our LPS–PbgA structure appears especially well accounted for by positive density peaks, and density consistent with a KDO sugar head group is also observed; and similar ...