Structure dependent selective efficacy of pyridine and pyrrole based Cu(II) Schiff base complexes towards in vitro cytotoxicity, apoptosis and DNA-bases binding in ground and excited stateMTT assayFACSUV-VisBinding isothermLaser flash photolysis
select article Pyrrole-hybridized spiro[chromeno[4,3-b]cycloalka[4,5]thieno[3,2-e]pyridine]cycloalkanes as modified tacrine system: Synthesis, structure, and photophysical evaluation Research articleAbstract only Pyrrole-hybridized spiro[chromeno[4,3-b]cycloalka[4,5]thieno[3,2-e]pyridine]cycloalkan...
An analysis of the results shows that the protonation on the end of the chain changes its nitrogen shielding constants of the pyridine and pyrrole type. These changes are much higher for the N(3)-H than for the N(1)-H tautomer. select article Periodic Hartree-Fock calculation of the A1g...
Changing the pyridine (from 1 and 2) and quinoline (from 3) moieties to a pyrrole (from 4), however, had a pronounced influence on metal-free Ab aggregation. Treatment of Ab40 with 4 produced aggregates that were 450 kDa in both inhibition and disaggregation samples, while increased ...
Zhang Y, Hörnfeldt AB, Gronowitz S, Stålhandske C.Pyridine-substituted hydroxythiophenes. III. Dimerization of 3-(2-pyridyl)thiophen-2(5H)-one from the demethylation reaction of 2-methoxy-3-(2-pyridyl)thiophene. X-ray structure determination of (±)-(3R*, 4S*)-3-(2-pyridyl)-4...
Crystal structure of 3,4-dimethyl-N'-(propan-2-ylidene)-1H-pyrrole-2- carbohydrazide, CHNO Crystal structure of catena-[dichlorido-μ-4,4’-dithiodipyridine-κ2N:N’- zinc(II)], CHClNSZn Crystal structure of 3,3'-(1,4-butanediyl-bis-(oxy-2,1-phenyleneimino)) bis-(1-metyl-2-...
All the chlorophyll molecules are characterized by the presence of four pyrrole-like rings (thus termed tetrapyrroles) along with an additional fifth ring. Besides, a number of side chains are attached to the ring structure, of which an important one is, the side chain of a long hydrocarbon,...
We have focused on the DNA polymerases involved in DNA replication including the unnatural base pair between 7-(2-thienyl)imidazo[4,5-b]pyridine (Ds) and 2-nitro-4-propynylpyrrole (Px). Many reports have described the different combinations between unnatural base pairs and DNA polymerases. As...
Herein, a new Zn(II)-based coordination polymer with formula [Zn(bpyp)(5-nip)] (1) (bpyp = 2,5-bis(pyrid-4-yl)pyridine and H2nip= 5-nitroisophthalic acid) has been synthesized and characterized. In 1, the two carboxyl groups of each 5-nip2− ligand adopts μ2-η1:η1 and...
(aminoethyl)pyridine (4-AEP) [81] with special functional groups such as -F, -COOH, -S-, and pyridine groups have been reported to create high-quality RPP films with high crystallinity, good crystallization orientation and decent phase composition. Noteworthy that these special functional groups ...