The functions of NAD(H) (NAD+ and NADH) and NADP(H) (NADP+ and NADPH) are undoubtedly significant and distinct. Hence, regulation of the intracellular balance of NAD(H) and NADP(H) is important. The key enzymes involved in the regulation are NAD kinase and NADP phosphatase. In 2000, ...
(a)∴(b)Both NAD and NADP are electron carriers that are used in respiration andphotosynthesis respectively.NAD is reduced during glycolysis,link reactionand Krebs cycle to form a total of 10 NADH.NADP is reduced duringphotophosphorylation to form NADPH.NADH donates electrons to the electrontranspor...
Background: Transhydrogenase, located in the inner membranes of animal mitochondria and the cytoplasmic membranes of bacteria, couples the transfer of reducing equivalents between NAD(H) and NADP(H) to proton pumping. The protein comprises three subunits termed dI, dII and dIII. The dII component...
For better understanding of the coenzyme specificity in NAD-dependent MDH (tMDH) from Thermus flavus AT-62, we determined the crystal structures of tMDH–NADP(H) complex at maximally 1.65 resolution. The overall structure is almost the same as that of the tMDH–NADH complex. However, NADP(...
Donaldson RP (1982) Nicotinamide cofactors (NAD and NADP) in glyoxysomes, mitochondria, and plastids isolated from castor bean endosperm. Arch Biochem Biophys 215: 274–279 PubMed CAS Google Scholar Donaldson RP, Beevers H (1977) Lipid composition of organelles from germinating castor bean endos...
ATP, cAMP, NAD+, NADP+, FAD, coenzyme A, etc. Adenosine triphosphate (ATP): ATP is the energy currency of the cell. The energy required for metabolic processes is derived from ATP. It also acts as a coenzyme and is a precursor of DNA and RNA synthesis. ATP Structure (Adenosine ...
The subunit structure and molecular weight of Escherichia coli NADP+-specific isocitrate dehydrogenase has been determined by polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate at pH 7.0 and in 8 M urea at pH 2.9. The results obtained indicate that the enzyme, which exists ...
1990 Primary structure of sorghum malate dehydrogenase (NADP) deduced from cDNA sequence. Homology with malate dehydrogenase (NAD) . European Journal of Biochemistry 192 : 299 – 303 .Crétin C, Luchetta P, Joly C, Decottignies P, Lepiniec L, Gadal P, Sallantin M, Huet JC and Pernollet ...
摘要: The iridoids have been widely used in pharmaceutical industry and integrated pest management.For better development of this valuable natural product,the enzyme that synthesize this compound was recently identified from Catharanthus roseus and named as iridoid synthase(IS).As a member of the...
Generally, a negative charged (Asp or Glu) residue at the end of the second β strand indicates that the enzyme is NAD(H)-preferred and this residue forms hydrogen bonds to the 2′ - and 3′ -hydroxyl group of the ade- nine ribose moiety23,24. NADP(H)-preferred enzymes possess ...