University of Minnesota Medical SchoolSpringer-VerlagChromosomaHozier JC, Furcht LT, Wendelshafer-Grabb G (1981) Structure of human chromosomes visualized at the electron microscope level. Chromosoma 82:55–64Hozier, J. C. , Furcht, L. T. and Wendelshafer-Grabb, G. 1981 . Structure of human ...
Molecular Structure of Human Chromosomes is an authoritative guide to genetics, focusing on human genome. This reference compiles contributions covering available knowledge on human genome structure and organization, which the previous researches fail to encompass. This text provides a comprehensive discussio...
Human Chromosomes: Structure, Behaviour, EffectsHuman Chromosomes: Structure, Behaviour, EffectsThe BJC is owned by Cancer Research UK, a charity dedicated to understanding the causes, prevention and treatment of cancer and to making sure that the best new treatments reach patients in the clinic as...
Because the human active and inactive X chromosomes differ in transcriptional activity and replication, we looked for differences in their chromatin loop structures. Since the islands of CpG-rich DNA at the 5' ends of X-linked housekeeping genes are the regions where functional differences in DNA ...
Binding occurred mainly in the regions of constitutive heterochromatin on chromosomes 1, 9, and 16, on the short arm of chromosome 15 and the midportion of the Y. The patterns were comparable to those observed by indirect immunofluorescence, but the immunoperoxidase technique appears to give ...
PBAF-NCP structure reveals a tripartite modular organization and is generally similar to the structures of nucleosome-bound human BAF13,14and yeast SWI/SNF and RSC complexes15,16,17,18(Fig.1b, Supplementary Fig.5). SMARCA4 serves as a central scaffold that involves formation of three modules....
The number of gyres, mode, and direction of coils, centromere, secondary constriction, and telomere were studied in the human somatic chromosomes in terms of spiral structure, employing the newly developed technique involving a hypotonic treatment. Results obtained are: 1. the number of gyres is ...
The mammalian sex chromosomes are composed of two genetically distinct segments: the pseudoautosomal region, where recombination occurs between the X and Y chromosomes, and the sex chromosome-specific parts. Between these two segments the human sex chromosomes differ by the insertion of an Alu element...
Since the announcement of the sequencing of the human genome 20 years ago1,2, human chromosomes have remained unfinished owing to large regions of highly identical repeats clustered within centromeres, regions of segmental duplication, and the acrocentric short arms of chromosomes. The presence of la...
Human telomerase is a RNA–protein complex that extends the 3′ end of linear chromosomes by synthesizing multiple copies of the telomeric repeat TTAGGG1. Its activity is a determinant of cancer progression, stem cell renewal and cellular aging2–5. Telo