Medium- and high-entropy alloys (M/HEAs) mix several principal elements with near-equiatomic composition and represent a model-shift strategy for designing previously unknown materials in metallurgy1,2,3,4,5,6,7,8, catalysis9,10,11,12,13,14 and other fields15,16,17,18. One of the core...
11), we calculate a half maximal activation tension of about 1.9 pN nm−1, matching experimentally measured values. Thus, our studies provide a fundamental understanding of how the notable deformability and structural rearrangement of PIEZO1 achieve exquisite mechanosensitivity and unique curvature-...
physics, chemistry, and biology have been connected by a web of causal explanation organized by induction-based theories that telescope into one another.…Thus, quantum theory underlies atomic physics, which is the foundation of reagent chemistry and its specialized offshoot biochemistry, which interlock...
We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with...
In C ++ 11, a derived class can reuse the constructor defined by its direct base class.class Derived : Base { public: using Base::Base; /* ... */ };As above using statement, for each constructor of the base class, the compiler generates a derived class constructor corresponding to it...
Structure-invariant direct methods were used for primary atom site locations, and secondary atom site locations were found from the difference Fourier map. The software used to prepare the material for publication was Mercury 2.3 (Build RC4) and ORTEP-3 [20,21]. The complete set of structural ...
Crystal structure of neutral endopeptidase (pdb-id: 1DMT), the only well characterized member opened new door to acquire structural knowledge of several members of this class of the protein[30]. The three-dimensional structure of ECE-1 was also solved with the co-crystallized metalloprotease ...
The human glucagon receptor, GCGR, belongs to the class B G-protein-coupled receptor family and plays a key role in glucose homeostasis and the pathophysiology of type 2 diabetes. Here we report the 3.0 Å crystal structure of full-length GCGR containing both the extracellular domain and tr...
Y.C. is an Investigator of Howard Hughes Medical Institute. A.M. acknowledges support from the Pew Charitable Trusts, the Esther and A. & Joseph Klingenstein Fund and the Searle Scholars Program. Author information Author notes Shane Gonen Present address: Department of Molecular Biology and ...
A waveguide structure formed with a three-dimensional (3D) photonic crystal is disclosed. The 3D photonic crystal comprises a periodic array of voids formed in a solid substrate. Th