Antibodies: Their structure and function (outline studies in biology): By M.W. StewardChapman and Hall, 1984. 96 pages (13.25) ISBN 0 412 25640 1doi:10.1016/0167-5699(84)90016-1JensSteensgaardSDOSImmunology Today
It allows a stoichiometrically higher number of antibodies to bind and thus increasing the neutralization efficiency (Fig. 9b and Supplementary Fig. 3). Consistent with this hypothesis, the BLI assay shows increased binding of NORO-320 to VLPs in the presence of EDTA (Fig. 6d). Similarly, the...
The featureless interface formed by protein–protein interactions (PPIs) is notorious for being considered a difficult and poorly druggable target. However, recent advances have shown PPIs to be druggable, with the discovery of potent inhibitors and stabilizers, some of which are currently being clinic...
On the other hand, a classical ELISA assay requires the application of two orthogonal antibodies of the analyte, which are not always easy to obtain [43]. In this study, we have substituted an ARC-inhibitor-based capture molecule for the capture antibody. ARC inhibitors are synthetic mid-...
The membranes were washed three times in TBS-T, then were incubated in Horse Radish Peroxidase (HRP) conjugated secondary antibody, 1:5000 anti-mouse (P044701-2, Agilent, Santa Clara, CA, USA) and 1:5000 anti-rabbit antibodies (P044801-2, Agilent). The membranes were developed by a ...
With 900 protein molecules, a total molecular weight of ∼72 MDa, and a diameter of ∼800 Å, our ISVP structure by single-particle cryo-EM represents the largest atomic structure ever determined by any structural biology techniques. Below, we first describe the finding of the auto...
Although present evidence indicates that anaphylaxis due to IgE antibodies does not involve the complement system, it has been established that complement participates in other forms of acute immunologic reactions as well as in the infl... HJ Müller-Eberhard - Springer US 被引量: 4发表: 1976年...
Electron microscope immunoperoxidase staining of rat liver nuclei with these antibodies labels exclusively the nuclear periphery. Furthermore, reaction occurs in... Gerace,L. - 《Journal of Cell Biology》 被引量: 782发表: 1978年 Establishment of a Novel Human Megakaryoblastic Leukemia Cell Line, ...
Intrahepatic assembly of very low density lipoproteins: immunologic characterization of apolipoprotein B in lipoproteins and hepatic membrane fractions and its intracellular distribution. Monoclonal antibodies, prepared against rat apoB, were used to examine apoB structure in serum lipoproteins and characterize...
forZmSUN5mRNA but low-level expression (50-200 parts per ten million) in multiple tissues for all the others. Cloning and characterization of a full-length cDNA for a PM3-type maize gene,ZmSUN4, is described. Peptide antibodies to ZmSUN3, 4 were used in western-blot and cell-staining ...