The primary structure of alcohol dehydrogenase from Drosophila lebanonensis: intensive variation within insect 'short-chain' alcohol dehydrogenase lacking zinc. Eur. J. Biochem. 180:191-197.Villarroya A, Juan E, Egestad B, Jfirnvall H (1989) The primary structure of alcohol dehydrogenase from ...
Substituent constants and regression analysis have been employed in a study of the structure-activity relationship of binding and inhibition of alcohol dehydrogenase with small molecules. Using this technique, it is possible to separate the hydrophobic, electronic, and steric roles of substituents in the...
HARRIS, I. 1964. Structure and catalytic activity of alcohol dehydrogenases. Nature 203:30-34.Harris, I. : Structure and catalytic activity of alcohol dehydrogenase . Nature (London) 1964 , 203 , 30 – 34 .Harris I. 1964 . Structure and catalytic activity of alcohol dehydrogenases . Nature ...
Trivic S, Leskovac V (2000) Structure and function of yeast alcohol dehydrogenase. J Serb Chem Soc 65:207–227Trivic, S.; Leskovac, V., Structure and function of yeast alcohol dehydrogenase. Journal of the Serbian Chemical Society, v. 65 (4), p. 207-227, 2000....
An alcohol dehydrogenase null activity allele, Adh nAH52 , extracted from a natural population of Drosophila melanogaster has been cloned and sequenced. Compared with the wild-type consensus sequence, the nucleotide sequence of Adh nAH52 contains eight extra bases in intron 2, adjacent to the 5'...
2.7 Å resolution structure of 82 kDa alcohol dehydrogenase We first decided to target the 82 kDa homodimeric enzyme alcohol dehydrogenase (ADH)15, as the structure of this complex had been previously determined to near-atomic resolution (e.g., better than 1.3 Å resolution) by ...
( 1984 ). Human liver alcohol dehydrogenase. The primary structure of the β' β' isoenzyme . Eur. J. Biochem. 145 , 437 – 445 .Hempel, J., Buhler, R., Kaiser, R., Holmquist, B., DeZalenski, C., von Wartburg, J.-P., Vallee, B. L., and Jornvall, H., Human liver ...
Our ~2.7 structure of alcohol dehydrogenase (82kDa) proves that bound ligands can be resolved with high fidelity to enable investigation of drug-target interactions. Our ~2.8 and ~3.2 structures of methemoglobin demonstrate that distinct conformational states can be identified within a dataset for ...
Crystallographic analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. alcohol dehydrogenase toward NADH cosubstrate specificity. Biotechnol. Bioeng. 110, 2803–2814 (2013). Article CAS PubMed Google Scholar Man, H. et al. Structures of alcohol dehydrogenases from Ralstonia and ...
The crystal structure analysis of horse liver alcohol dehydrogenase has been extended to 2.4 resolution. From the corresponding electron density map of the apoenzyme we have determined the positions of the 374 amino acids in the polypeptide chain of each subunit. The coenzyme binding domain of the ...